Analyzing Nursing Records in Wound Care Using a Large Language Model.

This study aimed to summarize unstructured nursing records on cancer wound management using a large language model (LLM) and assess the quality of these summaries. This retrospective descriptive study used 80 unstructured nursing records, which were generated from the documentation of specialized cancer wound care nurses. The analysis of the records consisted of four steps: 1) selecting 21 key variables based on British Columbia Cancer Agency guidelines, 2) using an LLM to summarize records according to these variables, 3) evaluating the quality of the summaries using both quantitative and qualitative assessment methods, and 4) categorizing errors in low-quality summaries.

High prevalence of -carrying in both ceftiofur-use and non-use pig farms.

Unlabelled: The emergence of third-generation cephalosporin-resistant bacteria poses a significant human health hazard worldwide. We aimed to investigate the prevalence of extended-spectrum β-lactamase (ESBL)/AmpC β-lactamase-producing third-generation cephalosporin-resistant in ceftiofur-use and non-use pig farms. A total of 585 isolates were collected from pig feces ( = 354) and farm environments ( = 231) across various farms between 2022 and 2023 in South Korea.

Measuring functioning and disability in Korea: comparing general and dedicated surveys using the ICF as a reference framework.

Introduction: Functioning is the third health indicator besides mortality and morbidity. Although Korea periodically collects functioning information, the functioning indicator has not been generated yet. This study aimed to evaluate how functioning information is currently collected in Korea's health and disability surveys, especially in terms of comparability and comprehensiveness, using the International Classification of Functioning, Disability and Health (ICF) as a reference framework.

Development of a functioning metric for the ageing population using data from the survey of health, ageing and retirement in Europe (SHARE).

Background: Beyond mortality and morbidity, health statistics would benefit from reporting information on functioning, the third health indicator. The objective of this article is to use data from the Swiss Survey of Health, Ageing and Retirement in Europe (SHARE) to exemplarily create a psychometrically sound and valid metric of functioning for the ageing population living in Switzerland.

Methods: Partial Credit Model (PCM) analysis, including analysis of targeting, item fit, local item dependencies (LID), unidimensionality, and differential item functioning (DIF), tested the psychometric properties of selected items.

Prevalence and characterization of ciprofloxacin-resistant spp. isolated from food animals during 2010-2023 in South Korea.

We isolated 6,561 strains from food animals, cattle ( = 217), pigs (= 1526), chickens ( = 3942), and ducks ( = 876). Isolates were evaluated for antimicrobial sensitivity, mutations in quinolone resistance determination regions (QRDRs), and plasmid-mediated quinolone resistance (PMQR) genes. Clonal relationship and genetic diversity were assessed by multi-locus sequence typing (MLST) and pulsed-field gel electrophoresis (PFGE).

Antimicrobial Resistance Profiles of Isolated from Food Animal Carcasses During 2010-2023 in South Korea.

Antimicrobial-resistant bacterial contamination of meat poses a significant global public health risk. We aimed to determine antimicrobial resistance profiles and trends of recovered from carcasses of healthy food-producing animals in South Korea during 2010-2023. In total, 4748 isolates obtained from cattle ( = 1582), pigs ( = 1572), and chickens ( = 1594) were assessed for susceptibility to 12 antimicrobials.

Comparative crystal structure analysis of the human EP300 and CBP KIX domains.

Small-cell lung cancer (SCLC) is highly lethal because the tumors grow and metastasize rapidly. Effective treatments for SCLC are lacking currently. A recent study demonstrated that the E1A binding protein P300 (EP300) KIX domain has pro-tumorigenic activity and is selectively involved in the development and growth of SCLC.

Overview of Available Functioning Data in Switzerland: Supporting the Use of Functioning as a Health Indicator Alongside Mortality and Morbidity.

Objectives: To identify official sources that routinely collect data on functioning in Switzerland, to provide an overview of the existing data and its comparability, and to assess the extent to which the data is suitable for developing a functioning metric and indicator.

Methods: Data sources were identified through an iterative search. Standardized rules were applied to map the functioning information assessed by the sources using a current WHO functioning and disability survey as a reference framework for the content comparison.

The Effect of Severe Varus Deformity on Clinical and Radiographic Outcomes in Mechanical Aligned Total Knee Arthroplasty with Medial Stabilizing Technique.

The purpose was to compare the clinical and radiographic outcomes between preoperative mild and severe varus deformity after total knee arthroplasty (TKA) with medial stabilizing technique (MST). We retrospectively analyzed 158 knees of 125 female patients with a 2-year follow-up who underwent mechanically aligned TKA with MST between April 2018 and February 2021. Patients were divided into two groups; the severe varus group was defined as one with preoperative hip-knee ankle (HKA) angle ≥ 15° and the mild varus group with HKA angle < 15°.

Lessons on harmonization of scoring criteria for dicentric chromosome assay in South Korea.

Purpose: Networking with other biodosimetry laboratories is necessary to assess the radiation exposure of many individuals in large-scale radiological accidents. The Korea biodosimetry network, K-BioDos, prepared harmonized scoring guidelines for dicentric chromosome assay to obtain homogeneous results within the network and investigated the efficiency of the guidelines.

Materials And Methods: Three laboratories in K-BioDos harmonized the scoring guidelines for dicentric chromosome assay.

Development of a Korean version of simple, intuitive descriptions for clinical use of the generic functioning domains in the ICD-11 Chapter V.

Purpose: To develop a Korean version of simple, intuitive descriptions (SIDs) for clinical use of the generic functioning domains in the International Classification of Disease 11 revision (ICD-11) Chapter V.

Methods: The initial Korean SID version proposal for the International Classification of Functioning, Disability, and Health (ICF) Rehabilitation set was translated following the Italian version. The remaining 17 codes were developed using original ICF descriptions; WHO Disability Assessment Schedule, Model Disability Survey, Korean Classification of Functioning, Disability, and Health; and previous studies.

Effect of structural variation in the promoter region of on the skin color of radish taproot.

Accumulation of anthocyanins in the taproot of radish is an agronomic trait beneficial for human health. Several genetic loci are related to a red skin or flesh color of radish, however, the functional divergence of candidate genes between non-red and red radishes has not been investigated. Here, we report that a novel genetic locus on the R2 chromosome, where .

TRIAD method to assess ecological risks of contaminated soils in abandoned mine sites.

Site-specific soil ecological risk assessment is important for protecting soil ecosystems because it reflects the environmental factors at the site to detect ecological risks and develop risk management measures. This study assessed the ecological risks from chemical pollutants in abandoned mine sites using the TRIAD approach, evaluating its overall applicability, including the tiered system of assessment. A site-specific soil ecological risk assessment was conducted for five abandoned mine sites (Sites 1-4 and R, the reference site); integrated risks (IRs) for each site were calculated.

Discovery of BET specific bromodomain inhibitors with a novel scaffold.

Bromodomain and extra-terminal domain (BET) proteins have been considered as potent candidates for anti-cancer drug development. As epigenetic readers, they modulate gene expression by recognizing acetylated lysine residues on histones. Therefore, the pharmacological inhibition of BET proteins has been extensively studied.

Site-specific ecological risk assessment of metal-contaminated soils based on the TRIAD approach.

Ecological risk assessment based on scientific data is crucial for understanding causal relationships between chemical pollution and environmental risks. Simultaneously, a balance is required between socioeconomic factors and scientific evidence. The TRIAD approach, which incorporates three lines of evidence (LoE)-chemical (Chem-LoE), ecotoxicological (Ecotox-LoE), and ecological (Eco-LoE)-was applied in five sites of an abandoned mine for site-specific soil ecological risk assessment (SERA).