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The global application of neonicotinoids (NEOs) has precipitated pervasive contamination of agricultural matrices, with China's staple crop lands representing critical exposure hotspots. The occurrence and ecological risks of ten NEOs in the field soils of three major crops (i.e., rice, wheat and corn) in China were investigated in the present study. Employing an optimized UPLC-MS/MS method (LOQ = 0.01-1.7 ng/g, RSD < 12.21%), ten NEOs across 69 representative field soils (rice: 23, corn: 18, wheat: 28) were quantified. It was found that the detection frequency (DF) of the NEOs was 100% in the soil. The DFs of NEOs in the soil followed the rule: imidacloprid (IMI, 100%) > thiamethoxam (TMX, 88.4%) > clothianidin (CLO, 87.0%) > acetamiprid (ACE, 46.4%) > dinotefuran (DIN, 7.2%) > nitenpyram (NIT, 1.4%). Mean total detected NEOs concentrations exhibited crop-dependent type: wheat (1.77-214.55 ng/g) > corn (0.79-97.53 ng/g) > rice (0.75-72.97 ng/g). The IMI, CLO and TMX triad constituted over 90% of the total contribution of detected NEOs. In addition, CLO and TMX in the rice soils, IMI, CLO and TMX in the corn soils and IMI, CLO and TMX in the wheat soils had medium ecological risks. Therefore, it is particularly important for agricultural ecological protection to strengthen monitoring and take effective measures to protect agricultural ecology.
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http://dx.doi.org/10.3390/molecules30081803 | DOI Listing |
Environ Pollut
October 2025
Instituto de Recursos Biológicos, Centro de Investigaciones de Recursos Naturales (CIRN). Instituto Nacional de Tecnología Agropecuaria (INTA), de los Reseros y N. Reppetto s/n, Hurlingham, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2320, Ciudad A
Thiamethoxam (TMX) is a neonicotinoid insecticide that is widely used for seed treatment in a variety of crops. Farmland birds can be exposed to TMX by consuming treated seeds remaining on the soil surface due to either spills or failed implantation during sowing. In the environment, TMX can be metabolized into clothianidin (CLO), another neonicotinoid insecticide that is also toxic to birds.
View Article and Find Full Text PDFMolecules
April 2025
Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China, Key Laboratory of Environment Friendly Management on Fruit and Vegetable Pests in North China (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Institute of Plan
The global application of neonicotinoids (NEOs) has precipitated pervasive contamination of agricultural matrices, with China's staple crop lands representing critical exposure hotspots. The occurrence and ecological risks of ten NEOs in the field soils of three major crops (i.e.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Nanjing Women and Children's Healthcare Institute, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing, China. Electronic address:
Background: Neonicotinoids (NEOs) are well-designed highly selective pesticides that target nicotinic acetylcholine receptors. However, their extensive use, accumulation, and biomagnification pose significant risks to humans. Increasing evidence has suggested that NEOs may affect glucose homeostasis, but little research has linked NEOs exposure to gestational diabetes mellitus (GDM), which is the most common disease in pregnancy.
View Article and Find Full Text PDFPestic Biochem Physiol
September 2024
College of Plant Protection, Yangzhou University, Jiangsu, Yangzhou 225009, China. Electronic address:
The widespread application of neonicotinoid insecticides (NNIs) has attracted widespread attention to their potential ecotoxicological effects. In this study, we systematically evaluated the toxic effects of thiamethoxam (TMX) and its metabolite clothianidin (CLO) on earthworms (Eisenia fetida). Specifically, the antioxidant system responses and endogenous metabolite metabolism responses in earthworms were analyzed in the temporal dimension after 7, 14, 21 and 28 days of exposure to TMX and CLO.
View Article and Find Full Text PDFEnviron Pollut
November 2024
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Shuangqing RD 18, Beijing, 100085, China. Electronic address: