Short-Path Hydrogen Spillover on CeO-Supported PtPd Nanoclusters for Efficient Hydrogen Evolution in Acidic Media.

Hydrogen spillover in supported metal electrocatalysts has garnered significant research attention for its potential to enhance the hydrogen evolution reaction (HER) efficiency. However, challenges remain in facilitating hydrogen spillover and reducing the associated energy barriers. Herein, PtPd alloy clusters are anchored to the CeO surface, enabling short-path hydrogen spillover and lowering the reaction energy barrier in acidic environments.

Pure Organic Thermally Activated Delayed Fluorescence Afterglow Polymers via Dopant Isomerization.

-(-Cyanophenyl)carbazole can be dimerized at different positions, which may change excited state behaviors. Herein, 2,3'-dicyano-3,4'-di(carbazol-9-yl)biphenyl (D34C) is designed and synthesized and doped into polymers. However, we find that D34C does not exhibit room temperature phosphorescence but emits fluorescence (FL) and bright thermally activated delayed fluorescence (TADF) with lifetimes of hundreds of milliseconds, which is observed in diverse matrices such as PMMA, MBS, ABS, PS, HIPS, and SIS.

Protocol for analyzing functional gene module perturbation during the progression of diseases using a single-cell Bayesian biclustering framework.

The pathogenesis of complex diseases involves intricate gene regulation across cell types, necessitating a comprehensive analysis approach. Here, we present a protocol for analyzing functional gene module (FGM) perturbation during the progression of diseases using a single-cell Bayesian biclustering (scBC) framework. We describe steps for setting up the scBC workspace, preparing and exploring input data, training the model, and reconstructing the data matrix.

Evaluating the toxicity effects of thiamethoxam and its main metabolite clothianidin to earthworms (Eisenia fetida) from the perspective of endogenous metabolites.

The widespread application of neonicotinoid insecticides (NNIs) has attracted widespread attention to their potential ecotoxicological effects. In this study, we systematically evaluated the toxic effects of thiamethoxam (TMX) and its metabolite clothianidin (CLO) on earthworms (Eisenia fetida). Specifically, the antioxidant system responses and endogenous metabolite metabolism responses in earthworms were analyzed in the temporal dimension after 7, 14, 21 and 28 days of exposure to TMX and CLO.

Investigating oral microbiome profiles in patients with cleft lip and palate compared with the healthy control.

Background: Patients with cleft lip and palate (CLP) have an oronasal communication differed from the closed state in healthy individuals, leading to a unique oral microbiome. This study aimed to determine if variances in the oral microbiota persist among CLP patients who have received treatments for the closure of these fistulas compared to the microbiota of healthy individuals.

Methods: Saliva samples were collected from a cohort comprising 28 CLP patients (CLP group) and 30 healthy controls (HC group).

Porphyromonas gingivalis OMVs promoting endothelial dysfunction via the STING pathway in periodontitis.

Objective: This study aimed to assess the effects of Porphyromonas gingivalis outer membrane vesicles (Pg-OMVs) in chronic periodontitis and explore the underlying mechanism involved.

Methods: In vitro, Pg-OMVs were incubated with Ea.hy926 (vessel endothelial cells, ECs) to evaluate their effects on endothelial functions and to investigate the underlying mechanism.

Development of the Static and Dynamic Gene Expression Regulation Toolkit in .

The advancement of metabolic engineering and synthetic biology has promoted in-depth research on the nonmodel microbial metabolism, and the potential of nonmodel organisms in industrial biotechnology is becoming increasingly evident. The nonmodel organism is a safe plant growth promoting bacterium for the production of phenazine compounds; however, its application is seriously hindered due to the lack of an effective gene expression precise regulation toolkit. In this study, we constructed a library of 108 promoter-5'-UTR (PUTR) and characterized them through fluorescent protein detection.

A geomagnetic vector compensation method compatible with nonlinear interferences based on back propagation network and 3D Helmholtz coil.

Magnetic interferential compensation plays a vital role in geomagnetic vector measurement applications. Traditional compensation accounts for only the permanent interferences, induced field interferences, and eddy-current interferences. However, nonlinear magnetic interferences are found, which also have a great impact on measurement, and it cannot be fully characterized by a linear compensation model.

NMR-based metabolomics approach to assess the ecotoxicity of prothioconazole on the earthworm (Eisenia fetida) in soil.

Prothioconazole (PTC) is a widely used agricultural fungicide. In recent years, studies have confirmed that it exerts adverse effects on various species, including aquatic organisms, mammals, and reptiles. However, the toxicological effects of PTC on soil organisms are poorly understood.

Azoxystrobin Disrupts Colonic Barrier Function in Mice Metabolic Disorders Mediated by Gut Microbiota.

The widespread use of azoxystrobin (AZO) over the past few decades has drawn great attention to its environmental health effects. The objective of the present study was to explore the effects of AZO on intestinal barrier function in mice from the perspective of gut microbiota. Specifically, exposure to AZO could cause colonic barrier dysfunction in mice.

On the Anisotropic Milling Machinability of DD407 Single Crystal Nickel-Based Superalloy.

The DD407 single crystal Ni-based superalloy with a face-centered cubic structure exhibits strong anisotropic characteristics. In order to reveal the material chip formation mechanism and the impact effect of crystal orientations on the materials' milling machinability, a combination of experimental observations and theoretical analysis were applied in this study. Considering the resolved shear stress and slip system theories, a fundamental theoretical explanation of the milling force and surface quality along different crystal directions on the (001) crystal plane of the DD407 single crystal Ni-based superalloy was proposed based on a previously constructed anisotropic milling model.

Human amnion-derived mesenchymal stem cells enhance the osteogenic differentiation of human adipose-derived stem cells by promoting adiponectin excretion via the APPL1-ERK1/2 signaling pathway.

Human adipose-derived stem cells (HASCs) represent pluripotent cells capable of differentiating into the bone tissue. Meanwhile, human amnion-derived mesenchymal stem cells (HAMSCs) could cause mesenchymal stem cells to differentiate into the bone tissue. This work assessed the osteogenic effects exerted by HAMSCs on the potential of HASCs to form bone cells.