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The error was noted after the publication of the article titled 'Nanotheranostics: The Fabrication of Theranostics with Nanoparticles and their Application to Treat the Neurological Disorders'', published in Recent Patents on Nanotechnology, 2025, 1, 17-34 [1], that a part of the text was inadvertently omitted. The missing text has now been included as: The original article can be found online at: https://www.eurekaselect.com/article/132973 We regret the error and apologize to readers. Details of the error and a correction are provided here. Original: Nanotheranostic However, we may encounter more significant difficulties with their in vivo studies by invalidating their safety and efficacy before clinical applications. Corrected: Nanotheranostic systems are being utilised in addition to imaging and treatment to track pharmacokinetics, the dispersion of particles in the tissue, and drug accumulation at the target site. Using this cutting-edge technology, a thorough understanding of the pathophysiology of neurological illnesses has been attained. The manufacture and physiochemical characterisation of nanotheranostics has been the main foci of notable in vitro studies in the current situation. However, we may encounter more significant difficulties with their in vivo studies by invalidating their safety and efficacy before clinical applications.
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http://dx.doi.org/10.2174/187221051902250224124215 | DOI Listing |
Int J Pharm X
December 2025
Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University Uttar Pradesh, Sector-125, Noida 201313, India.
Intestinal inflammation particularly inflammatory bowel disease poses significant clinical challenges due to its chronic nature, limited treatment efficacy and adverse effects of conventional therapies like corticosteroids and biologics. Biomimetic nanocarriers have emerged as a transformative strategy to overcome these limitations by leveraging natural cell membranes for targeted drug delivery. This review critically examines the application of biomimetic nanocarriers as precision therapeutics for intestinal inflammation.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
Department of Sports Medicine, The First Affiliated Hospital, Guangdong Provincial Key Laboratory of Speed Capability, The Guangzhou Key Laboratory of Precision Orthopedics and Regenerative Medicine, Jinan University, Guangzhou, Guangdong, China.
Introduction: During the healing process, the functional gradient attachment of the rotator cuff (RC) tendon-bone interface fails to regenerate, which severely impedes load transfer and stress dissipation, thereby increasing the risk of retears. As a result, the treatment of rotator cuff tears remains a significant clinical challenge.
Methods: In this study, a dual-crosslinked hyaluronic acid/polyethylene glycol (HA/PEG) hydrogel scaffold was synthesized using hyaluronic acid and polyethylene glycol as base materials.
Mater Today Bio
October 2025
Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Organ-on-a-chip (OoC) systems can simulate the key functions of human organs, combining microfluidics, cell culture, and biomaterials. 3D printing can be integrated into these technologies to facilitate the construction of OoC models. The high precision and layer-by-layer fabrication process of 3D printing not only enables the creation of complex structures for the microfluidic chip but also improves the cellular microenvironment within the chip by harnessing bioinks for 3D bioprinting.
View Article and Find Full Text PDFElectrophoresis
September 2025
School of Mechanical Engineering, Jiangsu Key Laboratory for Design and Manufacturing of Precision Medicine Equipment, Southeast University, Nanjing, China.
Electric droplet sorting is widely applied in the screening of target molecules, cells, drugs, and microparticles. Previous studies have made several optimizations on the electrode materials, structures, and arrangements. However, voltages of over 1 kV are required to realize droplet sorting, which causes the undesired droplet splitting.
View Article and Find Full Text PDFAnn Biomed Eng
September 2025
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Purpose: Replicating spinal cord injury (SCI) in large animals is necessary for evaluating translational therapeutics, yet there is currently no commercial, standardized device for inducing SCI. We present the fabrication and testing of a custom impactor device for producing repeatable contusion SCI in porcine models.
Methods: The device was built, and mechanical modeling was utilized for calibration.