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This article investigates an adaptive prescribed performance path-following control algorithm for rotor-assisted vehicles, incorporating reinforcement learning (RL) to execute energy-saving cruising missions. For obtaining a high-performance path-following controller, a concise prescribed performance control (PPC) algorithm is designed to tightly constrain the output errors within the defined boundaries, while a shifting function is introduced to solve the problem of initial condition restrictions. Furthermore, through integrating the Backstepping method and the optimal control technique, an improved RL with the form of actor-critic neural networks (AC-NNs) is proposed to offer an innovative approach to the challenges of the model uncertainties and external disturbances. In this approach, the actor NN is employed to create an appropriate control policy, while the critic NN is aimed at evaluating the cost-to-go function to modify the system action. Semi-global uniform ultimate bounded (SGUUB) stable properties of the proposed algorithm are guaranteed via the Lyapunov theory. Finally, the superiority and feasibility of the proposed algorithm are verified by two numerical experiments.
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http://dx.doi.org/10.1109/TNNLS.2025.3562245 | DOI Listing |
J Neurooncol
September 2025
Department of Radiation Oncology, Massachusetts General Hospital, Boston, USA.
Purpose: Cranial irradiation is associated with health-related quality of life (HRQoL) deficits in childhood cancer survivors. We investigated the relationship between radiation dose to brain substructures and HRQoL in children with brain tumors treated with proton beam therapy (PBT).
Methods: Data were obtained from children in the Pediatric Proton/Photon Consortium Registry who received PBT for primary brain tumors between 2015 and 2021.
Cancer Med
September 2025
Department of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Introduction: In the past decade, the management of advanced prostate cancer has shifted to novel hormonal therapies. As a result, urologists have increased their involvement in the management of advanced prostate cancer. These therapies require close monitoring due to the possibility of adverse cardiometabolic events.
View Article and Find Full Text PDFJ Adv Nurs
September 2025
School of Health and Social Care, Edinburgh Napier University, Edinburgh, UK.
Aim: To examine the extent of adherence to high-level principles in remote prescribing and investigate how medical and non-medical prescribers comply with these principles.
Design: Scoping Review.
Data Sources: A systematic search of CINAHL, PubMed, Medline, the Cochrane Database of Systematic Reviews, the Web of Science, and the Ovid Emcare databases was performed.
Medicine (Baltimore)
September 2025
Department of Cardiology, Jining Key Laboratory of Metabolic Cardiovascular Diseases, Institute of Cardiovascular Diseases of Jining Medical Research Academy, Jining No. 1 People's Hospital, Jining, Shandong, China.
Rationale: Myocardial infarction with nonobstructive coronary arteries (MINOCA) has diverse ischemic etiologies and has been defined by the absence of angiographically significant obstructive coronary artery disease. Blood transfusion has seldom been reported as a precipitating factor for MINOCA. Here, we present a rare case of transfusion-associated MINOCA in a young woman without underlying chronic conditions, aiming to raise clinical awareness of this uncommon yet important phenomenon and to explore its potential pathophysiological mechanisms.
View Article and Find Full Text PDFRadiat Oncol
September 2025
Department of Breast Sarcoma and Endocrine Tumors, Karolinska University Hospital, Stockholm, Sweden.
Background: Stereotactic Body Radiotherapy (SBRT) has been proven to be a safe and effective alternative to surgery in patients with metastatic primary sarcoma. However, data describing tumor response in relation to the given radiotherapy dose is lacking. Therefore, this study aims at analyzing efficacy and dose-response relationship in a retrospective cohort.
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