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Background: Advancements in three-dimensional mapping systems have enhanced the precise accessory pathway (AP) localization and conduction properties. However, accurately identifying the earliest atrial or ventricular activation sites remains challenging, particularly in cases with multiple insertions or epicardial connections.
Case Summary: A 24-year-old woman with palpitations and a manifest Wolff-Parkinson-White syndrome Type A underwent catheter ablation. Local activation time mapping revealed extensive conduction in the posterior mitral annulus, with a peak frequency (PF) of 291 Hz at the earliest ventricular and earliest atrial activation sites on the endocardium in the omnipolar technology near field (OTNF) mapping. The coronary sinus and middle cardiac vein were additionally mapped using an ablation mapping catheter and a 1.6-Fr electrode catheter. Emphasis mapping identified the Kent bundle location during right ventricular pacing using local activation time and PF mapping. A narrower region of atrial insertion at the entrance of the middle cardiac vein was revealed, with a PF of 645 Hz. The AP connection successfully disappeared 8 s after ablation to the entrance of the middle cardiac vein. At the 3-month follow-up, the patient showed no recurrence of delta waves on the electrocardiogram or related symptoms.
Discussion: The novel OTNF concept further enhances this function by differentiating far-field potentials based on annotated PFs. The use of PF values with novel OTNF mapping proved valuable in identifying optimal target sites for the ablation of APs. The combination of OTNF mapping and advanced ablation catheters may enable the precise targeting of specific AP sites.
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http://dx.doi.org/10.1093/ehjcr/ytaf181 | DOI Listing |
Lipids Health Dis
September 2025
Epidemiology, Medical Faculty, University of Augsburg, Stenglingstr. 2, Augsburg, 86156, Germany.
Background: This study aimed to investigate the gender-specific associations of skeletal muscle mass and fat mass with non-alcoholic fatty liver disease (NAFLD) and NAFLD-related liver fibrosis in two population-based studies.
Methods: Analyses were based on data from the MEGA (n = 238) and the MEIA study (n = 594) conducted between 2018 and 2023 in Augsburg, Germany. Bioelectrical impedance analysis was used to evaluate relative skeletal muscle mass (rSM) and SM index (SMI) as well as relative fat mass (rFM) and FM index (FMI); furthermore, the fat-to-muscle ratio was built.
BMC Cardiovasc Disord
September 2025
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Sociology and Rehabilitation Science, Charitéplatz 1, 10117, Berlin, Germany.
Background: Myocardial infarctions (MI) significantly contribute to the global disease burden and are often followed by psychological conditions such as depression, anxiety, and posttraumatic stress disorder (PTSD). These are frequently underrecognized and insufficiently addressed in clinical care. This study aims to investigate the psychosocial impact of MI, identify risk factors for psychological burden following an MI, and gain insight into the perceived psychological care during hospitalization.
View Article and Find Full Text PDFAnn Biomed Eng
September 2025
Department of Mechanical Engineering, Koc University, Rumeli Feneri Campus, Sarıyer, 34450, Istanbul, Turkey.
Purpose: The design and development of ventricular assist devices have heavily relied on computational tools, particularly computational fluid dynamics (CFD), since the early 2000s. However, traditional CFD-based optimization requires costly trial-and-error approaches involving multiple design cycles. This study aims to propose a more efficient VAD design and optimization framework that overcomes these limitations.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 210032, China.
Antisynthetase syndrome(ASS) is an entity among the immune inflammatory myopathies(IIM), which always affects lungs. Interstitial lung disease(ILD) is common in ASS, while pulmonary hypertention(PH)is rarely observed. In this paper, we reported a case of ASS with ILD and PH.
View Article and Find Full Text PDFJMIR Hum Factors
September 2025
Media Psychology Lab, Department of Communication Science, KU Leuven, Leuven, Belgium.
Background: Out-of-hospital cardiac arrests (OHCAs) are a leading cause of death worldwide, yet first responder apps can significantly improve outcomes by mobilizing citizens to perform cardiopulmonary resuscitation before professional help arrives. Despite their importance, limited research has examined the psychological and behavioral factors that influence individuals' willingness to adopt these apps.
Objective: Given that first responder app use involves elements of both technology adoption and preventive health behavior, it is essential to examine this behavior from multiple theoretical perspectives.