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Recent research on Polycystic Ovary Syndrome (PCOS) detection increasingly employs intelligent algorithms to assist gynecologists in more accurate and efficient diagnoses. However, intelligent PCOS detection faces notable challenges: absence of standardized feature taxonomies, limited research on available datasets, and insufficient understanding of existing detection tools' capabilities. This paper addresses these gaps by introducing a novel analytical framework for PCOS diagnostic research and developing a comprehensive taxonomy comprising 108 features across 8 categories. Furthermore, we analyzed available datasets and assessed current intelligent detection tools. Our findings reveal that 12 publicly accessible datasets cover only 54% of the 108 features identified in our taxonomy. These datasets frequently lack multimodal integration, regular updates, and clear license information-constraints that potentially limit detection tool development. Additionally, our analysis of 42 detection tools identifies several limitations: high computational resource requirements, inadequate multimodal data processing, insufficient longitudinal analysis capabilities, and limited clinical validation. Based on these observations, we highlight critical challenges and future research directions for advancing intelligent PCOS detection tools.
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http://dx.doi.org/10.1016/j.csbj.2025.04.011 | DOI Listing |
Fluids Barriers CNS
September 2025
Department of Medical Sciences, Neurology, Uppsala University, Uppsala, Sweden.
Background: Idiopathic normal pressure hydrocephalus (iNPH) predominantly manifests with gait disturbances, yet clinical assessments are vulnerable to confirmation bias, particularly post-shunt surgery. Blinded video evaluations are a method to enhance objectivity in gait assessment, but their reliability has never been systematically investigated. The aim was to evaluate the inter-rater reliability of blinded gait assessments in iNPH patients and to investigate how these assessments correlate with the Hellström iNPH scale and patient-reported health status following shunt surgery.
View Article and Find Full Text PDFMetabolomics
September 2025
Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France.
Introduction: Initially developed for transcriptomics data, pathway analysis (PA) methods can introduce biases when applied to metabolomics data, especially if input parameters are not chosen with care. This is particularly true for exometabolomics data, where there can be many metabolic steps between the measured exported metabolites in the profile and internal disruptions in the organism. However, evaluating PA methods experimentally is practically impossible when the sample's "true" metabolic disruption is unknown.
View Article and Find Full Text PDFBDJ Open
September 2025
Operative Dentistry & Endodontics, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Background: Artificial Intelligence (AI) has become increasingly integrated into dental diagnostics, particularly for detecting carious lesions. While AI offers benefits such as improved accuracy and efficiency, its use raises important ethical concerns, including transparency, patient privacy, autonomy, diversity and accountability. This scoping review aims to identify these ethical concerns using a structured ethical framework.
View Article and Find Full Text PDFSci Rep
September 2025
Paleoanthropology Section, Department of Geosciences, Institute for Archaeological Sciences, University of Tübingen, Tübingen, Germany.
Human communication is remarkable for its flexibility, a trait largely reflected in its multimodal nature and shared to some extent with nonhuman primates. Although individual differences in social behaviour are known to have evolutionary implications, their role in shaping primate communication remains largely unexplored. This study adopts a multimodal framework to partition variation in chimpanzees' use of multicomponent and multisensory communicative strategies into socio-environmental, between-individual, and within-individual sources.
View Article and Find Full Text PDFGastroenterol Hepatol
September 2025
Department of Gastroenterology, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), University of Barcelona. Barcelona, Catalonia, Spain. Electronic address:
Objective: The primary goal of a public health system is to ensure universal access to high-quality medical care. However, disparities in health outcomes have been observed across socio-demographic groups, some of them potentially related to their geographical location. To assess territorial equity, the Catalan Colorectal Cancer Screening Program was used, focusing on the adenoma detection rate (ADR) endoscopists.
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