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Purpose: To propose a method to effectively reduce radiation dose while enhancing image quality in chest CT for patients unable to elevate their arms utilizing the air-gap technique.
Methods: Chest CT images were acquired in three positions: arms raised (control group, position A), arms lowered with the air-gap technique utilizing an in-house device (position B), and arms lowered without the device (position C). Data were categorized by body weight. Radiation dose was assessed using dose-length product (DLP) values, with quantitative analyses of image noise, contrast-to-noise ratio (CNR), and CNR-to-dose ratio (CNRDR). Qualitative assessment utilized a Likert scale.
Results: Average DLP was 473.7 ± 142.9 mGy × cm in position C, with the lowest in position A at 267.3 ± 93.3 mGy × cm. Position B had a DLP of 317.2 ± 121.4 mGy × cm, 18.7 % higher than position A but 33.0 % lower than position C. In patients over 70 kg, all positions exceeded the thoracic CT diagnostic reference level (DRL) (324.2 mGy × cm). For those under 70 kg (i.e., <50 kg, 50-70 kg), position B showed lower DLPs compared to the above DRL. Quantitative analysis indicated that position B maintained image quality similar to position A, with CNRDR of 30.2 ± 11.1 versus 26.6 ± 10.9 in position A, showing marginal significance (p = 0.046). The qualitative evaluation indicated that position A had the highest rating at 4.96, followed by position B at 4.51, and position C at 3.47.
Conclusion: The air-gap device with lowered arms during chest CT for patients unable to elevate their arms can reduce radiation dose while maintaining image quality. A custom-designed device facilitates safe and efficient procedures, especially for patients with higher body weight.
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http://dx.doi.org/10.1016/j.ejrad.2025.112120 | DOI Listing |
J Magn Reson Imaging
September 2025
School of Biomedical Engineering, Guangdong Provincial Key Laboratory of Medical Image Processing and Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China.
Background: The dynamic progression of gray matter (GM) microstructural alterations following radiotherapy (RT) in patients, and the relationship between these microstructural abnormalities and cortical morphometric changes remains unclear.
Purpose: To longitudinally characterize RT-related GM microstructural changes and assess their potential causal links with classic morphometric alterations in patients with nasopharyngeal carcinoma (NPC).
Study Type: Prospective, longitudinal.
J Cancer Res Clin Oncol
September 2025
Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Targeted intraoperative radiotherapy (IORT) delivers a single dose of radiation to a fresh tumour bed immediately after lumpectomy, commonly used to treat early breast cancer (EBC). It is delivered during the same sitting, with improved patient compliance and better sparing of adjacent healthy tissue, compared to conventional adjuvant radiotherapy to the whole breast. The recently published 12-year results (median follow up of 8.
View Article and Find Full Text PDFRadiat Environ Biophys
September 2025
Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Sodium orthovanadate (vanadate), a potent inhibitor of p53, has been shown in earlier work to alleviate total-body irradiation (TBI)-induced hematopoietic syndrome. However, as p53 plays a crucial role in normal spermatogenesis, its suppression may raise concerns about potential adverse effects on male reproductive function. In this study, we investigated whether vanadate exacerbates impairment of male fertility when administered for hematopoietic protection under TBI conditions.
View Article and Find Full Text PDFHealth Phys
September 2025
Nuclear and Radiological Engineering and Medical Physics Programs, George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA.
External exposure due to secondary photons (predominantly bremsstrahlung) generated from electron source emissions in environmental soil are of concern due to their ability to deposit significant amounts of ionizing energy to organs and tissues within the body. The "condensed history method" employed in many modern Monte Carlo (MC) codes may be used to simulate secondary photon yields (given as photons per beta decay) arising from electron source emissions with relatively few assumptions regarding the secondary photon spatial, energy, and angular dependencies. These yields may in turn be used to derive protection quantities such as secondary photon effective dose rate (DR) and risk coefficients for a variety of idealized external exposure scenarios.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Percutaneous transthoracic lung biopsy (PTNB) guided by Computed Tomography (CT) greatly depends on the operators' skill for accuracy. This study aimed to evaluate whether three-dimensionally(3D) printed navigational templates for percutaneous transthoracic lung biopsy achieve diagnostic yield comparable to conventional computed tomography guidance.
Materials And Methods: Conducted from 1 November 2020, to 27 July 2023, this noninferiority randomized clinical trial included 159 patients with peripheral lung masses (≥30 mm).