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Visual adaptation is one of the most significant features that helps organisms process complicated image information in time-varying environments. Emulating this function is highly desirable for energy-efficient image perception. In this work, we demonstrate an yttrium oxide (YO)-based optoelectronic memristor and emulate photopic adaptation behavior in a single device. Decay amplitude and photosensitivity are indexed to describe the time-dependent characteristics of photopic adaptation. An intensity-dependent characteristic, namely Weber's law, is also investigated in this work. Photopic adaptation originates from the trapping of photogenerated carriers in oxygen vacancies. Based on photopic adaptation behavior, a neuromorphic vision system capable of adapting to environmental brightness is constructed using the proposed optoelectronic memristor array. Memristor arrays can emulate sensing and adaptation functions in order to enhance images against bright backgrounds. Our work provides a feasible pathway toward self-adaptive neuromorphic vision systems.
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http://dx.doi.org/10.3390/nano15080579 | DOI Listing |
Sci Rep
August 2025
Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, 21287, USA.
Electroretinography (ERG) is pivotal in elucidating retinal function, yet investigations into the temporal dynamics of ERG signals in New Zealand White (NZW) and Dutch-belted (DB) rabbits remain scarce. This study presents a longitudinal assessment of retinal function in both NZW and DB strains. ERG recordings were conducted on four NZW and four DB rabbits at 2, 7, 15, and 24 months of age, encompassing both dark-adapted and light-adapted protocols at each time point.
View Article and Find Full Text PDFIndian J Ophthalmol
September 2025
Department of Cataract and Vitreoretinal Services M. N Eye Hospital, Chennai, Tamil Nadu, India.
Purpose: To evaluate the efficacy and safety of 1.25% pilocarpine compared to placebo for the treatment of presbyopia.
Methods: This multicenter, randomized, double-masked clinical trial compared pilocarpine 1.
Am J Ophthalmol
August 2025
Department of Ophthalmology and Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany.
Purpose: To investigate the presence of hypertransmission (HT) in normal aging, early (e)AMD, and intermediate (i)AMD, changes over 3 years, and the impact of HTs ≥ 250 µm (LHyperTD) on seven tests of scotopic, mesopic, and photopic vision.
Design: Prospective cohort study.
Subjects: Participants of the Alabama Study on Early Age-Related Macular Degeneration 2.
Doc Ophthalmol
August 2025
Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC, 3002, Australia.
Purpose: The Celeris system (Diagnosys LLC) offers a streamlined alternative to the gold-standard Espion system for high-throughput electroretinography (ERG) and visual evoked potentials (VEP) in preclinical studies. This study evaluated its inter-session repeatability of ERG and VEP measurements in healthy rodent retinae.
Methods: Twenty-five wild type Brown Norway rats underwent ERG and VEP testing across two sessions.
Sci Rep
August 2025
Great Ormond Street Institute of Child Health, University College London, London, UK.
This study aims to evaluate if the reduced sensitivity to global motion observed in some individuals with autism spectrum disorder (ASD) is associated with altered retinal processing. Motion coherence thresholds were measured from individuals with ASD and their family members and compared to the test reference limits derived from control participants. The light adapted electroretinogram (ERG) a- and b-wave amplitudes and peak-times, and photopic negative response (PhNR) parameters were measured from the ASD individuals and their families and compared to those of controls.
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