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Improving the prediction skill of El Niño-Southern Oscillation (ENSO) is of critical importance for society. Over the past half-century, significant improvements have been made in ENSO prediction. Recent studies have shown that deep learning (DL) models can substantially improve the prediction skill of ENSO compared to individual dynamical models. However, effectively integrating the strengths of both DL and dynamical models to further improve ENSO prediction skill remains a critical topic for in-depth investigations. Here, we show that these DL forecasts, including those using the Convolutional Neural Networks and 3D-Geoformer, offer comparable ENSO forecast skill to dynamical forecasts that are based on the dynamic-model mean. More importantly, we introduce a combined dynamical-DL forecast, an approach that integrates DL forecasts with dynamical model forecasts. Two distinct combined dynamical-DL strategies are proposed, both of which significantly outperform individual DL or dynamical forecasts. Our findings suggest the skill of ENSO prediction can be further improved for a range of lead times, with potentially far-reaching implications for climate forecasting.
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http://dx.doi.org/10.1038/s41467-025-59173-8 | DOI Listing |
Arq Gastroenterol
September 2025
State University of Campinas, Faculty of Medical Sciences, Department of Surgery, Digestive Diseases Surgical Unit - Campinas (SP), Brazil.
Background: Gastroesophageal reflux disease has a prevalence of 12% in the Brazilian population. Its treatment includes hygienic-dietary changes, use of medications and, in selected cases, surgery with laparos-copic hiatoplasty and Nissen total fundoplication. However, this last treatment modality presents risks of postoperative dysphagia.
View Article and Find Full Text PDFBull Math Biol
September 2025
Department of Mathematics, Siena University, 515 Loudon Road, Loudonville, NY, 12211, USA.
Autonomous differential equation compartmental models hold broad utility in epidemiology and public health. However, these models typically cannot account explicitly for myriad factors that affect the trajectory of infectious diseases, with seasonal variations in host behavior and environmental conditions as noteworthy examples. Fortunately, using non-autonomous differential equation compartmental models can mitigate some of these deficiencies, as the inclusion of time-varying parameters can account for temporally varying factors.
View Article and Find Full Text PDFBackground: Adolescents with autism spectrum disorder (ASD) often experience identity confusion, social difficulties, and internalizing symptoms such as anxiety and depression. Physical activity offers opportunities for peer interaction and teamwork, which may help alleviate negative emotions. This study aims to investigate the pathways through which physical activity influences internalizing problems in adolescents with ASD.
View Article and Find Full Text PDFInt Emerg Nurs
September 2025
Professor, School of Health & Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Melbourne, Australia. Electronic address:
Background: ST-segment elevation myocardial infarction (STEMI) demands aggressive and rapid medical intervention. Delays in Door-to-balloon time (DTB) of more than 90 min cause progressive damage to the cardiac tissue and require immediate medical intervention, including percutaneous coronary intervention (PCI). Nurses and doctors in STEMI management face several challenges that result in a delay in DTB time.
View Article and Find Full Text PDFMed Sci Sports Exerc
September 2025
Department of Engineering Mechanics, Tsinghua University, Beijing, CHINA.
Purpose: Develop a musculoskeletal-environment interaction model to reconstruct the dynamic-interaction process in skiing.
Methods: This study established a skier-ski-snow interaction (SSSI) model that integrated a 3D full-body musculoskeletal model, a flexible ski model, a ski boot model, a ski-snow contact model, and an air resistance model. An experimental method was developed to collect kinematic and kinetic data using IMUs, GPS, and plantar pressure measurement insoles, which were cost-effective and capable of capturing motion in large-scale field conditions.