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Purpose: To devise an implementation blueprint for the fracture liaison service (FLS) model within the context of a medical consortium. The FLS is an integrated system designed to identify, register, assess, treat, and monitor patients with osteoporotic fractures. The FLS constitutes a structured intervention strategy to administer standardized care to osteoporotic fracture patients. Its efficacy has been validated through extensive implementation across various countries. However, large-scale intervention research on this model within China is lacking. This investigation endeavors to construct a comprehensive FLS framework and to establish its core performance indicators within the Chinese medical alliance structure.
Patients And Methods: The research methodology encompassed focus group interviews and a two-phase Delphi process. An initial inventory of FLS implementation elements was compiled through a systematic literature review and focus group discussions. This was followed by a two-step Delphi survey, wherein experts refined the key indicators. The study calculated metrics such as response rate, composite reliability (CR), coefficient of variation, and the Kendall coefficient of concordance to evaluate the indicators.
Results: The study involved 17 experts who completed 2 rounds of the Delphi consultation, culminating in a consensus on 2 primary and 8 secondary indicators, encompassing 34 specific indicators. The response rate for the first and second round was 100%, with CR values of 0.871 and 0.882, and Kendall's coefficients of 0.161 and 0.179, respectively ( < 0.05).
Conclusion: This work delineated a robust set of indicators specifically tailored for the FLS schema under the medical alliance framework in China. The rigorous application of the Delphi technique led to a consensus on 34 pivotal indicators, elucidating their relative significance.
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http://dx.doi.org/10.2147/JMDH.S481843 | DOI Listing |
Qual Life Res
September 2025
The Kids Research Institute Australia, The University of Western Australia, P.O. Box 855, West Perth, WA, 6872, Australia.
Purpose: CDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Greater understanding of the smallest meaningful improvements for individuals with CDD in clinical trials and practice is needed for a person-centred approach to treatment efficacy. This study explored how parent/caregivers of people with CDD understood meaningful improvements and described change for priority functional domains including communication, gross motor, fine motor, feeding.
View Article and Find Full Text PDFAnesthesiology
October 2025
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.
Despite the widespread use of clinical anesthesia, the process of emergence from general anesthesia remains primarily driven by anesthetic elimination. Although emergence from general anesthesia is typically safe, prolonged delays strain resource-intensive settings and contribute to increased healthcare costs. In addition to improving access to care, providing clinicians with more precise control over emergence could offer diagnostic potential and improve patient outcomes.
View Article and Find Full Text PDFTrauma Surg Acute Care Open
September 2025
UCHealth, University of Colorado Health, Loveland, Colorado, USA.
Introduction: Trauma is the leading cause of death among individuals aged 1-44 years, and it is estimated that many of these deaths could be prevented. Clinical guidance is an essential step toward the optimization of trauma care, especially within rural environments. This qualitative case series seeks to better understand how trauma clinical guidance (TCG) plays a role in rural trauma providers' patient management.
View Article and Find Full Text PDFGlob Health Action
December 2025
Institute for Global Health, University College London, London, UK.
Background: In a cluster-randomised trial in Uganda and Tanzania, we showed that integrated management, compared with standard vertical care, could achieve a high standard of care for diabetes and hypertension without adversely affecting outcomes for HIV. However, evidence on the value for money of integrated care is needed to inform policy.
Objective: Our economic evaluation aimed to establish the value for money of integrated care compared with vertical care for HIV, diabetes and hypertension.
Arch Sex Behav
September 2025
University of Groningen, University Medical Center Groningen, Department of Psychiatry, Hanzeplein 1, 9700 RB, Groningen, The Netherlands.