Odontogenic brain abscess caused by and : a case report and review article.

J Oral Microbiol

Department of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Published: April 2025


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Article Abstract

Background: Odontogenic brain abscess is a rare, but potentially fatal, central nervous system infection, with insidious onset and unclear etiology.

Methods: This case reports a 70-year-old male patient who developed an odontogenic brain abscess secondary to periodontal infection and underwent neurological surgery. Extract pus during surgery for the metagenomic next-generation sequencing (mNGS).

Results: The mNGS of pus samples obtained from brain abscess aspiration identified the periodontal pathogens and . Consequently, he was referred to the department of stomatology for further examination and treatment.

Conclusions: Our study found that major periodontal pathogens including and were essential in the development of odontogenic brain abscesses; thus, timely intervention and preventive measures are important for treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001842PMC
http://dx.doi.org/10.1080/20002297.2025.2485197DOI Listing

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