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Pesticides play a crucial role in modern agriculture, yet they pose considerable risks to soil health and ecosystem integrity. Current risk assessment research often relies on simplified models, focusing on single substances under standardized conditions and failing to reflect realistic exposure scenarios. We call for a paradigm shift toward incorporating agroecological research that evaluates pesticide effects under more complex and dynamic conditions, including mixtures, application frequency, diverse soil properties, and interactions with other environmental stressors. Additionally, multiseasonal exposure and long-term persistence of pesticides in soils must be considered. By integrating these multidimensional factors, such experimental research can yield valuable insights that improve environmental risk assessment frameworks, ensuring they more accurately represent the complexity of agricultural systems and support more sustainable soil management practices.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046603 | PMC |
http://dx.doi.org/10.1021/acs.jafc.4c12818 | DOI Listing |
Brain Imaging Behav
September 2025
Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, South 4th Ring West Road 119, Fengtai District, Beijing, 100070, China.
To explore the effect of brain cognitive compensation on the pathogenesis of postoperative delirium (POD) in the frontal glioma patients. Eighty-four adult patients with unilateral frontal glioma who underwent elective craniotomy and 37 healthy controls were recruited. Primary outcomes were POD during postoperative 1-7 days, as assessed by Confusion Assessment Method.
View Article and Find Full Text PDFGeroscience
September 2025
Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan, 3004, 1081 LA, Amsterdam, the Netherlands.
The increasing prevalence of overweight/obesity among the elderly has significant implications for oral health due to shared pathophysiological mechanisms. Despite its importance, comprehensive reviews on this topic remain limited. This study investigates the association between overweight/obesity and oral health outcomes in adults aged 55 and older.
View Article and Find Full Text PDFJ Epidemiol
September 2025
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University.
Background: The potential impacts of polygenic scores (PGS) on health-behavior changes are not fully understood. The Iwate PGS Assessment and Risk Communication Study aims to investigate the effects of reporting PGS-based risk for ischemic stroke on health behaviors.
Methods: Participants wishing to know their PGS-based ischemic stroke risk were recruited from health checkup venues for workers in Iwate Prefecture in 2023.
J Cyst Fibros
September 2025
Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, USA.
Recent improvements in cell-free DNA technology have enabled non-invasive prenatal testing (NIPT) to screen for fetal single-gene autosomal recessive conditions from maternal blood as early as the first trimester. This technique can determine the fetal risk for cystic fibrosis (CF) with a single blood sample from a pregnant person without the need for a partner sample, which is required for traditional carrier screening. A retrospective review of 100,106 consecutive general-risk pregnant patients who underwent CF carrier screening was completed.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Anhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, School of Resource & Environment, Anhui Agricultural University, Hefei, Anhui 230036, China; Institute of Ecological Environmental Protection and Pollution Remediation Engineering, Anhui Agricultural U
Neonicotinoid insecticides residuals pose a threat to aquatic ecosystems and human health. Imidaclothiz, as a novel neonicotinoid pesticide, the metabolic mechanisms in aquatic environments was unclear. This study investigated the degradation characteristics of imidaclothiz in both pure and actual water, and analyzed the photodegradation and hydrolysis metabolites of imidaclothiz in aquatic environments and assessed their toxicity.
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