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With the development of new materials and the trend of miniaturization of smart devices, wearable devices are playing an increasingly important role in people's lives and occupying a larger market share. Meanwhile, the operation of wearable devices is based on the flexible sensors inside them. Although the development of flexible sensors has been very rapid in the more than 20 years since entering the 21st century, facing the booming market and demand at present, the development of flexible sensors still faces many challenges such as more miniaturization, higher integration, greater sustainability, high precision, and more efficient energy saving. This paper aims to summarize the development of flexible sensors, look forward to the future development of such devices, and provide a reference for researchers.
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http://dx.doi.org/10.3390/nano15070520 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
Agonist-induced interaction of G protein-coupled receptors (GPCRs) with β-arrestins (βarrs) is a critical mechanism that regulates the spatiotemporal pattern of receptor localization and signaling. While the underlying mechanism governing GPCR-βarr interaction is primarily conserved and involves receptor activation and phosphorylation, there are several examples of receptor-specific fine-tuning of βarr-mediated functional outcomes. Considering the key contribution of conformational plasticity of βarrs in driving receptor-specific functional responses, it is important to develop novel sensors capable of reporting distinct βarr conformations in cellular context.
View Article and Find Full Text PDFNanomicro Lett
September 2025
Nanomaterials & System Lab, Major of Mechatronics Engineering, Faculty of Applied Energy System, Jeju National University, Jeju, 63243, Republic of Korea.
Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring, clinical diagnosis, and robotic applications. Nevertheless, it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility, adhesion, self-healing, and environmental robustness with excellent sensing metrics. Herein, we report a multifunctional, anti-freezing, self-adhesive, and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes (CoN CNT) embedded in a polyvinyl alcohol-gelatin (PVA/GLE) matrix.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
School of Mechanical & Automotive Engineering, South China University of Technology, Guangzhou, 510641, China.
Recently, flexible airflow sensors have attracted significant attention due to their impressive characteristics and capabilities for airflow sensing. However, the development of high-performance flexible airflow sensors capable of sensing airflow over large areas remains a challenge. In this work, it is proposed that a hair-like flexible airflow sensor, based on laser direct writing and electrostatic flocking, offers an efficient technology for airflow sensing.
View Article and Find Full Text PDFAdv Mater
September 2025
Key Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education, School of Physics and Electronics, Hunan Normal University, Changsha, 410081, China.
The high sensitivity and wide linearity are crucial for flexible tactile sensors in adapting to diverse application scenarios with high accuracy and reliability. However, conventional optimization strategies of constructing microstructures suffer from the mutual restriction between the high sensitivity and wide linearity. Herein, a novel design of localized gradient conductivity (LGC) with partly covered low-conductivity (low-σ) carbon/Polydimethylsiloxane layer on high-conductivity (high-σ) silver nanowires film upon the micro-dome structure is proposed.
View Article and Find Full Text PDFSmall
September 2025
Shaanxi Key Laboratory of Chemical Additives for Industry, College of Chemistry and Chemical Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China.
Conductive hydrogels have significant application prospects in the field of flexible wearable sensors. However, there are still challenges to stably apply conductive hydrogels in extreme environments and various aqueous conditions. To enable the application of conductive hydrogels across a wide temperature range and in multiple environments, it is necessary to consider comprehensive properties such as anti-swelling ability, flexibility, self-adhesiveness, stable linear sensing, and certain durability.
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