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http://dx.doi.org/10.1016/j.jid.2025.03.025 | DOI Listing |
Biol Trace Elem Res
September 2025
Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science
The uncharted effects of cadmium and cesium on circadian syndrome (CircS), an emerging circadian rhythm disorder drawing considerable attention, and underlying mechanisms warrant exigent elaboration. Data of 11141 subjects from National Health and Nutrition Examination Survey 2005-2018 were incorporated to investigate separate-, joint-/interaction-, and mixture-effects of urinary cadmium and cesium on prevalent CircS risk exploiting survey weight regression and quantile g-computation. The underlying mechanisms were probed by network toxicological analysis.
View Article and Find Full Text PDFDent Mater J
September 2025
Biomaterials Lab, Dentistry School, Federal University of Pará.
This study evaluated the chemical profile of toothpastes (TPs) and mouthrinses (MRs) and their effects on tooth enamel ultrastructure, and the viability of human dental pulp fibroblasts (hDPF). Four TPs and MRs containing different remineralizing agents (arginine, potassium nitrate, pro arginine, and stannous chloride) were analyzed for pH, titratable acidity (TA), and ion concentrations (Ca, K, Na). Enamel ultrastructure was evaluated using Fourier-transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM).
View Article and Find Full Text PDFEnviron Health Prev Med
September 2025
Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, University of Toyama.
Background: Hyperthermia (HT), while a cancer treatment approach, isn't always effective alone. Therefore, identifying hyperthermia enhancers is crucial. We demonstrated that Mito-TEMPO ([2-[(1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) amino]-2-oxoethyl]-triphenylphosphanium, MT) acts as a potent thermosensitizer, promoting cell death in human cervical cancer (HeLa) cells.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Marine College, Shandong University, Weihai, Shandong 264209, China. Electronic address:
Tralopyril (TP), a representative bromopyrrolonitrile, functions as a broad-spectrum insecticide, raising growing concerns about its potential impact on aquatic organisms and human intestinal health. However, the key targets and toxicity mechanisms underlying TP-induced enteritis remain unclear. In this study, we utilized network toxicology combined with molecular docking to comprehensively explore the potential molecular mechanisms underlying TP-induced enteritis.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
College of Life Sciences, Chongqing Normal University, Chongqing, China; Key Laboratory of Pollinator Resources Conservation and Utilization of the Upper Yangtze River, Ministry of Agriculture and Rural Affairs, Chongqing, China; Chongqing Key Laboratory of Vector Control and Utilization, Chongqing,
As key pollinators, bees are increasingly threatened by environmental stressors such as heavy metals, pesticides, and temperature fluctuations, which can cause oxidative stress and disrupt cellular homeostasis. Glutathione S-transferases (GSTs) play crucial roles in antioxidant defense and detoxification, yet systematic studies on bee GST families remain limited. Here, we conducted a genome-wide analysis of cytosolic GST genes in 13 bee species, identifying 146 genes in total.
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