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Background: Hemodynamically unstable pelvic ring injuries pose significant challenges in trauma care. Although external fixation is traditionally used for initial stabilization, pelvic binders have emerged as potential alternatives. Therefore, this study aimed to evaluate the feasibility and safety of maintaining pelvic binders alone as a temporary stabilization method in patients with hemodynamically unstable pelvic ring injuries.
Methods: This retrospective cohort study included 114 patients with hemodynamically unstable pelvic ring injuries treated at two Level 1 trauma centers. The patients were divided into two groups: Binder-Only (n = 53) and External Fixation (n = 61). Outcomes including complications, intensive care unit (ICU) length of stay, and mechanical ventilation duration were compared.
Results: Baseline characteristics and injury severity were comparable between the two groups. There were no significant differences in complication rates (22.6% vs. 26.2%, p = 0.657), ICU length of stay (8 [3-16] vs. 10 [6-19] days, p = 0.257), or mechanical ventilation duration (3 [1-6] vs. 5 [2-9] days, p = 0.098) between the Binder-Only and External Fixation groups. The Binder-Only group achieved anterior fixation earlier than the External Fixation group (2 [1-2] vs. 4 [2-5] days, p < 0.001). Logistic regression analysis confirmed that group allocation was not associated with complications. The independent predictors of complications included diabetes mellitus, initial lactate level, and packed red blood cells transfusion within 4 h.
Conclusions: Pelvic binders provide sufficient temporary stabilization in hemodynamically unstable pelvic ring injuries, with outcomes comparable to those of external fixation. This strategy offers a practical alternative that avoids the complications and logistical challenges associated with external fixation.
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http://dx.doi.org/10.1007/s00402-025-05849-1 | DOI Listing |
J Perinatol
September 2025
Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Objective: To quantify agreement between oscillometric non-invasive blood pressure (NIBP) and invasive arterial blood pressure (IBP) in infants <500 g during the first postnatal week.
Study Design: Retrospective cohort of infants with a birth weight <500 g admitted to a tertiary NICU (2011-2023). Paired IBP-NIBP readings obtained within 1 min were analyzed.
Cardiol Cardiovasc Med
August 2025
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.
Deep vein thrombosis (DVT) and pulmonary embolism (PE) are key initiating events in the development of venous thromboembolism (VTE), a condition associated with significant morbidity, mortality, and long-term complications. While traditional therapies have focused on anticoagulation and thrombolysis, current evidence describes the pivotal role of immune pathways in the pathogenesis and progression of thrombosis. This review explores the multifaceted mechanisms underlying DVT and PE, emphasizing the contribution of inflammation, leukocyte activation, and immuno-thrombosis to thrombus formation and embolization.
View Article and Find Full Text PDFSemin Dial
September 2025
Department of Nephrology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Background: In hyponatremic patients, concurrent dialysate flow during hemodialysis may be an ideal option to mitigate complications such as osmotic demyelination syndrome (ODS).
Methods: Present randomized controlled trial enrolled dialysis-requiring chronic kidney disease (CKD) and acute kidney injury (AKI) patients with serum sodium levels < 125 mEq/L during January 2020 over 16 months. Hemodynamically unstable patients, as well as those with a history of seizures and neurological conditions, were excluded.
J Physiol
September 2025
Faculty of Medicine, Department of Pathophysiology, Masaryk University, Brno, Czech Republic.
Severe aortic stenosis (AS) is a recognized risk factor for sudden cardiac death (SCD). Although ventricular tachyarrhythmias are the most common immediate cause of SCD, the majority of cases of SCD in patients with severe AS exhibited bradyarrhythmia as the primary rhythm. Enhanced activation of left ventricular baroreceptors (Bezold-Jarisch reflex) has been implicated in the pathogenesis of syncope in patients with AS.
View Article and Find Full Text PDFCardiovasc Intervent Radiol
September 2025
Second Department of Radiology, School of Medicine, National and Kapodistrian University of Athens, 'Attikon' University General Hospital, 1 Rimini Str, 12462, Haidari/Athens, Greece.