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Many benign bone lesions mimic skeletal metastases from thyroid cancer on imaging and even may have high metabolic uptake on F-FDG PET/CT. It becomes crucial to distinguish these hypermetabolic lesions (benign vs. metastasis), especially in patients with thyroglobulin elevation and negative iodine scan. The index case describes a patient with thyroid cancer having thyroglobulin elevation and negative iodine scan with a hypermetabolic aneurysmal bone cyst mimicking skeletal metastasis.
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http://dx.doi.org/10.2967/jnmt.124.269415 | DOI Listing |
Pol Merkur Lekarski
September 2025
BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE.
Objective: Aim: To find out new objective criteria for laser histological differential diagnosis of thyroid pathology based on the use of a digital method of layer-by-layer polarization-interference mapping of polarization ellipticity maps of microscopic images of native histological sections of thyroid biopsy.
Patients And Methods: Materials and Methods: Four groups of patients were studied: control group 1 - healthy donors (51 patients); study group 2 - patients with nodular goiter (51 patients); study group 3 - patients with autoimmune thyroiditis (51 patients); study group 4 - patients with papillary cancer (51 patients). Methods used: polarization-interference, statistical.
Inflamm Res
September 2025
Department of General Surgery, Beijing Anzhen Hospital, Capital Medical University, No.2 Anzhen Road, Chaoyang District, Beijing, 100029, China.
Background: The roles of long non-coding RNAs (lncRNAs) in the progression of various human tumors have been extensively studied. However, their specific mechanisms and therapeutic potential in Triple-Negative Breast Cancer (TNBC) remain to be fully elucidated.
Materials And Methods: The qRT-PCR assay was utilized to assess the relative mRNA levels of TFAP2A-AS1, PHGDH, and miR-6892.
Ann Med
December 2025
Department of Thyroid Oncology, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, P.R. China.
Front Nutr
August 2025
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Background: Voghera pepper (VP) extracts were demonstrated to have anti-oxidant ability in several cell types.
Purpose: This study aimed to assess whether VP-extracts could lower oxidative stress and modulate thyroid cancer (TC) cells behavior .
Methods: Extracts were analyzed using the LC-DAD-MS system.
Front Endocrinol (Lausanne)
September 2025
Department of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Marburg, Germany.
Introduction: The prognosis of anaplastic thyroid carcinoma (ATC) remains poor. Mutation-based targeted therapies and immune checkpoint inhibitors (ICI) have gained increasing importance in the treatment of advanced tumor stages. This study aimed to investigate whether mutation-based neoadjuvant therapy can convert an initially unresectable tumor into a resectable state, optimizing local tumor control and prolonging overall survival.
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