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Article Abstract
Objective: To explore and quantify the association of hot night exposure during the sperm development period (0-90 lag days) with semen quality.
Methods: A total of 6,640 male sperm donors from 6 human sperm banks in China during 2014-2020 were recruited in this multicenter study. Two indices (i.e., hot night excess [HNE] and hot night duration [HND]) were used to estimate the heat intensity and duration during nighttime. Linear mixed models were used to examine the association between hot nights and semen quality parameters.
Results: The exposure-response relationship revealed that HNE and HND during 0-90 days before semen collection had a significantly inverse association with sperm motility. Specifically, a 1 °C increase in HNE was associated with decreased sperm progressive motility of 0.0090 (95% confidence interval [ ]: -0.0147, -0.0033) and decreased total motility of 0.0094 (95% : -0.0160, -0.0029). HND was significantly associated with reduced sperm progressive motility and total motility of 0.0021 (95% : -0.0040, -0.0003) and 0.0023 (95% : -0.0043, -0.0002), respectively. Consistent results were observed at different temperature thresholds on hot nights.
Conclusion: Our findings highlight the need to mitigate nocturnal heat exposure during spermatogenesis to maintain optimal semen quality.
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| http://dx.doi.org/10.3967/bes2024.131 | DOI Listing |
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