Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1093/ndt/gfae291DOI Listing

Publication Analysis

Top Keywords

normalization dynamics
4
dynamics donor-derived
4
donor-derived cell-free
4
cell-free dna
4
dna predicts
4
predicts future
4
future kidney
4
kidney transplant
4
transplant rejection
4
normalization
1

Similar Publications

Analyzing the toxicological effects of PET-MPs on male infertility: Insights from network toxicology, mendelian randomization, and transcriptomics.

Reprod Biol

September 2025

Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, No 218 Jixi Road, Hefei Anhui230022, China; Key Laboratory of Population Health Across

Current research indicates that polyethylene terephthalate microplastics (PET-MPs) may significantly impair male reproductive function. This study aimed to investigate the potential molecular mechanisms underlying this impairment. Potential gene targets of PET-MPs were predicted via the SwissTargetPrediction database.

View Article and Find Full Text PDF

Dopamine (DA) signaling is essential for neurodevelopment and is particularly sensitive to disruption during adolescence. Protein restriction (PR) can impair DA dynamics, yet mechanistic insights remain limited due to challenges in real-time neurochemical sensing. Here, we present aptCFE, a robust implantable aptamer-based sensor fabricated via a reagent-free, 3 min electrochemical conjugation (E-conjugation) using amine-quinone chemistry.

View Article and Find Full Text PDF

Protein translation regulation is critical for cellular responses and development, yet how elongation stage disruptions shape these processes remains incompletely understood. Here, we identify a single amino acid substitution (P55Q) in the ribosomal protein RPL-36A of Caenorhabditis elegans that confers complete resistance to the elongation inhibitor cycloheximide (CHX). Heterozygous animals carrying both wild-type RPL-36A and RPL-36A(P55Q) develop normally but show intermediate CHX resistance, indicating a partial dominant effect.

View Article and Find Full Text PDF

Detecting Many-Body Scars from Fisher Zeros.

Phys Rev Lett

August 2025

East China Normal University, Key Laboratory of Polar Materials and Devices (MOE), School of Physics and Electronic Science, Shanghai 200241, China.

The far-from-equilibrium dynamics of certain interacting quantum systems still defy precise understanding. One example is the so-called quantum many-body scars (QMBSs), where a set of energy eigenstates evade thermalization to give rise to long-lived oscillations. Despite the success of viewing scars from the perspectives of symmetry, commutant algebra, and quasiparticles, it remains a challenge to elucidate the mechanism underlying all QMBS and to distinguish them from other forms of ergodicity breaking.

View Article and Find Full Text PDF

Dimensionality-Driven Anomalous Metallic State with Zero-Field Nonreciprocal Transport in Layered Ising Superconductors.

Phys Rev Lett

August 2025

Nanjing University, National Laboratory of Solid State Microstructures, Institute of Brain-Inspired Intelligence, School of Physics, Collaborative Innovation Center of Advanced Microstructures, Nanjing 210093, China.

The anomalous metal state (AMS), observed in "failed" superconductors, provides insights into superconductivity and quantum criticality, with studies revealing unconventional quantum phases like the Bose metal. Recently, layered transition metal dichalcogenide (TMD) superconductors approaching the two-dimensional limit have garnered significant attention for the enhanced phase fluctuations and electronic correlations. Investigating AMSs in these systems, particularly in the absence of an external magnetic field, could offer valuable insights into the dimensionality-driven emergence of exotic quantum phenomena, including triplet Cooper pairing, phase fluctuation dynamics, and especially the recently discovered field-free superconducting diode effects.

View Article and Find Full Text PDF