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The development of micro glucose sensors plays a vital role in the management and monitoring of diabetes, facilitating real-time tracking of blood glucose levels. In this paper, we developed a three-layer core-sheath microwire (NW@CuO@CoO) with nickel wire as the core and copper oxide and cobalt oxide nanowires as the sheath. The unique core-sheath structure of microwire enables it to have both good conductivity and excellent electrochemical catalytic activity when used as an electrode for glucose detecting. The non-enzymatic glucose sensor base on a NW@CuO@CoO core-sheath wire exhibits a high sensitivity of 4053.1 μA mM cm, a low detection limit 0.89 μM, and a short response time of less than 2 s.
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http://dx.doi.org/10.3390/nano15060411 | DOI Listing |
Nanoscale
September 2025
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu 215123, China.
The rational design and synthesis of one-dimensional hierarchical heterojunction materials for high-performance electrocatalytic applications present an enticing prospect in the field of electrochemistry. Herein, barnyardgrass-like CuO/CuO/SnO branched supernanowires were rationally designed and controllably prepared a synergistic process of co-precipitation and microwave treatment to achieve highly sensitive non-enzymatic glucose sensors. These prepared CuO/CuO/SnO ternary hierarchical heterostructures possessed a specific surface area of 102.
View Article and Find Full Text PDFAntioxidants (Basel)
August 2025
Department of Cardiovascular Biomedicine, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.
Reductive stress (RS) results from the overactivity of the enzymatic and non-enzymatic antioxidant systems and from excess antioxidant agents that neutralize reactive oxygen species. (HSL) is a natural source of antioxidant molecules that can overload the antioxidant system. Twenty-one Wistar rats were divided into three groups: group 1 (G) G1: rats that consumed a 6% HSL infusion for one month (HSL + 6%), G2: rats that consumed a 6% HSL infusion for one month and were then given natural water for another month (HSL ± 6%), and G3: rats with natural drinking water.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
CardiacData Analytics, Winter Park, FL, United States.
Introduction: Cardiovascular aging starts early in life due to the glycation of critical proteins, though its progression remains undetected in the formative years. The glycation reaction affects all tissues by the same non enzymatic irreversible reaction. The variables are the pH, temperature, glucose concentration, and the specific protein.
View Article and Find Full Text PDFTalanta
August 2025
School of Electronic Information Engineering, Changchun University of Science and Technology, Changchun, Jilin, 130022, PR China. Electronic address:
Herein, a novel synthetic method is proposed to obtain hollow few-layer TiCT nanosheets@Ni-Fe layered double hydroxide microrods (TiCT@NiFe-LDH), which includes the coating process of MIL-88A microrods by two-dimensional TiCT nanosheets, the pre-adsorption process of 2-methylimidazole on the surfaces of MIL-88A@TiCT microrods, and the co-precipitation process of Ni and Fe with the interlayer of fumaric acid anions, resulting in the unique material structure of TiCT@NiFe-LDH. More importantly, hollow microrods composed of TiCT and NiFe-LDH nanosheets show the structural advantages, which are responsible for the high-performance behaviors towards the non-enzymatic detection of glucose, leading to 0.5-115.
View Article and Find Full Text PDFBiosensors (Basel)
August 2025
BioMark@UC/CEMMPRE (Centre for Mechanical Engineering, Materials and Processes)-ARISE (Advanced Production and Intelligent Systems), Faculty of Sciences and Technology, Department of Chemical Engineering, University of Coimbra, 3030-790 Coimbra, Portugal.
This work describes a non-enzymatic electrochemical glucose biosensor combining for the first time molecularly imprinted polymers (MIPs) for glucose concentration and gold nanoparticles (AuNPs) on screen-printed carbon electrodes (SPEs), where both MIPs and AuNPs were assembled in situ. Electrochemical impedance spectroscopy (EIS) was used to evaluate the analytical performance of the sensor, which has a linear range between 1.0 µM and 1.
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