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Recent advancements in model pruning have focused on developing new algorithms and improving upon benchmarks. However, the practical application of these algorithms across various models and platforms remains a significant challenge. To address this challenge, we propose ONNXPruner, a versatile pruning adapter designed for the ONNX format models. ONNXPruner streamlines the adaptation process across diverse deep learning frameworks and hardware platforms. A novel aspect of ONNXPruner is its use of node association trees, which automatically adapt to various model architectures. These trees clarify the structural relationships between nodes, guiding the pruning process, particularly highlighting the impact on interconnected nodes. Furthermore, we introduce a tree-level evaluation method. By leveraging node association trees, this method allows for a comprehensive analysis beyond traditional single-node evaluations, enhancing pruning performance without the need for extra operations. Experiments across multiple models and datasets confirm ONNXPruner's strong adaptability and increased efficacy. Our work aims to advance the practical application of model pruning.
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http://dx.doi.org/10.1109/TPAMI.2025.3554560 | DOI Listing |
IEEE Trans Pattern Anal Mach Intell
September 2025
Transformers have been successfully applied in the field of video-based 3D human pose estimation. However, the high computational costs of these video pose transformers (VPTs) make them impractical on resource-constrained devices. In this paper, we present a hierarchical plug-and-play pruning-and-recovering framework, called Hierarchical Hourglass Tokenizer (HOT), for efficient transformer-based 3D human pose estimation from videos.
View Article and Find Full Text PDFNeural Netw
September 2025
Dept. of CSE, Konkuk University, Seoul, 05029, Republic of Korea. Electronic address:
Neural network compression problems have been extensively studied to overcome the limitations of compute-intensive deep learning models. Most of the state-of-the-art solutions in this context are based on network pruning that identify and remove unimportant weights, filters or channels. However, existing methods often lack actual speedup or require complex pruning criteria and additional training (fine-tuning) overhead.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
State Key Laboratory of Membrane Biology, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Although clinical research has revealed microglia-related inflammatory and immune responses in bipolar disorder (BD) patient brains, it remains unclear how microglia contribute to the pathogenesis of BD. Here, we demonstrated that Serinc2 is associated with susceptibility to BD and showed a reduced expression in BDII patient plasma, which correlated with the disease severity. Using induced pluripotent stem cell (iPSC) models of sporadic and familial BDII patients, we found that Serinc2 expression showed deficits in iPSC-derived microglia-like cells, resulting in decreased synaptic pruning.
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
August 2025
College of Information Engineering, Sichuan Agricultural University, Ya'an 625014, China.
Objectives: We propose a YOLOv11-TDSP model for improving the accuracy of dental abnormality detection on panoramic oral X-ray images.
Methods: The SHSA single-head attention mechanism was integrated with C2PSA in the backbone layer to construct a new C2PSA_SHSA attention mechanism. The computational redundancy was reduced by applying single-head attention to some input channels to enhance the efficiency and detection accuracy of the model.
ACS Chem Neurosci
September 2025
School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Glial cells play an indispensable role in the nervous system, providing structural support to neurons and regulating their function and development. Glia support neural network formation and plasticity in axon guidance, synaptic pruning, and neurogenesis. Of note, studies have shown that glial cell dysfunction is closely related to the occurrence of neurological diseases.
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