Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

The spin Hall effect of light (SHEL), the transverse splitting of light into two circularly polarized components via refraction or reflection, offers high-precision, nondestructive inspection of unknown interfaces when combined with a signal amplification technique called weak measurement. However, its application in detecting dynamics is limited due to its multistep process. Here, we condense the procedure into a single step, enabling calibration-free, single-shot measurement of the SHEL by replacing one component of the conventional setup with a polarization beamsplitting metasurface. Our approach allows for instantaneous evaluation of the SHEL, even with fluctuations in the original beam position. As proof of concept, we apply metasurface-assisted weak measurements to both static and dynamic scenarios, where the experimental results obtained from a single captured image demonstrate nice agreement with theory. This real-time observation of the SHEL highlights its potential for high-precision monitoring of dynamic processes such as biomedical sensing and chemical analysis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923185PMC
http://dx.doi.org/10.1038/s41467-025-56728-7DOI Listing

Publication Analysis

Top Keywords

real-time observation
8
spin hall
8
hall light
8
weak measurements
8
observation spin
4
light metasurface-enabled
4
metasurface-enabled single-shot
4
single-shot weak
4
measurements spin
4
shel
4

Similar Publications

Rheumatoid arthritis (RA) is a chronic autoimmune disease in which dysregulated interferon regulatory factor 5 (IRF5) may amplify pro-inflammatory pathways; prior genetic studies of IRF5 single-nucleotide variants (SNVs) in RA are inconsistent across populations and have not included mestizo Mexicans or evaluated rs59110799 in RA. We aimed to test whether four IRF5 SNVs (rs2004640G/T, rs2070197T/C, rs10954213G/A, rs59110799G/T) confer susceptibility to RA in women from Central Mexico. In a case-control study of 239 women with RA and 231 female controls (all self-identified Mexican-Mestizos, ≥3 generations), genotyping was performed by real-time PCR with TaqMan® probes; 80% of samples were duplicated (100% concordance) and control genotypes conformed to Hardy-Weinberg equilibrium.

View Article and Find Full Text PDF

Despite significant advancements in the treatment of non-small cell lung cancer (NSCLC) using conventional therapeutic methods, drug resistance remains a major factor contributing to disease recurrence. In this study, we aimed to explore the potential benefits of combining PI3K inhibition with Cisplatin in the context of NSCLC-derived A549 cells. Human non-small cell lung cancer A549 cells were cultured and treated with BKM120, cisplatin, or their combination.

View Article and Find Full Text PDF

Objectives: Excessive neuroinflammatory responses represent a key pathological mechanism in cerebral small vessel disease (CSVD). Dl-3--butylphthalide (NBP), a compound previously demonstrated to possess anti-inflammatory properties in ischemic stroke, was investigated for its potential therapeutic effects in a rodent model of CSVD. This study aimed to elucidate the neuroprotective mechanisms of NBP in CSVD pathogenesis.

View Article and Find Full Text PDF

Background: Azygos vein aneurysm (AVA) is a rare thoracic pathology that is frequently misdiagnosed. While contrast-enhanced chest computed tomography (CT) or magnetic resonance imaging (MRI) can delineate AVA location and size, these techniques lack the capability for dynamic real-time assessment of internal architecture.

Case Presentation: We present a highly unusual case of a 67-year-old woman who had an isolated azygos vein aneurysm presenting with dysphagia.

View Article and Find Full Text PDF

Introduction: Ovarian cancer has a high mortality rate due to late diagnosis, relapse and chemoresistance. miRNAs play a major role in tumorigenesis as well as chemoresistance. Hence, we undertook a study, to evaluate the differential expression of miRNAs in clinical specimens of ovarian cancer patients that may highlight the effect of chemotherapy and their role in predicting survival outcomes.

View Article and Find Full Text PDF