AGEs in cooked meat: Production, detection, and mechanisms of its inhibition by plant extracts.

Food Res Int

State Key Laboratory of Agricultural Products Safety, Ningbo University, Ningbo 315211, China; College of Food Science and Engineering, Ningbo University, Ningbo, Zhejiang 315211, China. Electronic address:

Published: April 2025


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Article Abstract

With the growing demand for food safety and nutrition, the challenge of ensuring the quality of cooked meat products while reducing the accumulation of AGEs during processing needs urgent attention. In this study, the patterns of AGEs production, detection methods, quality contribution, and molecular mechanisms of its inhibition by natural plant-based extracts (NPBE) in cooked meat products were comprehensively reviewed. NPBE can effectively reduce the accumulation of AGEs in meat by binding to AGEs precursors and reducing glycosylation sites. It has also been shown to significantly remove off-flavour, and inhibit protein carbonylation. The potential for synergistic inhibition of AGE formation using NPBE and exogenous physical field treatments such as pulsed electric fields, microwave irradiation, thermal cycling of air, and ultrasound was emphasized, as well as the urgent need for the development of portable AGE detectors integrated with artificial intelligence and big data analytical models. This study indicates the future research direction for inhibiting the generation of AGEs in cooked meat products, which can promote and guide the practical application of NPBE in cooked meat products.

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http://dx.doi.org/10.1016/j.foodres.2025.116067DOI Listing

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