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Hair health critically influences both aesthetic appearance and psychological well-being. Existing treatments often show limited efficacy and may cause side effects. (GP), known for its antioxidant and anti-inflammatory properties, has emerged as a promising botanical agent, although clinical evidence regarding its hair health benefits remains limited. This study aimed to evaluate the efficacy and safety of GP extract in improving hair parameters through a randomized controlled trial. This randomized, double-blind, placebo-controlled trial involved 100 eligible adults aged 19-60 years who were randomly allocated to either the GP or placebo group. Participants consumed 340 mL/day of the test product for 24 weeks. The primary outcomes included hair elasticity, density, diameter, glossiness, and subjective satisfaction. Safety was evaluated through laboratory tests and adverse event monitoring. After 24 weeks, the GP group showed a threefold increase in hair elasticity and density and a fourfold increase in hair diameter compared to the placebo group. The subjective satisfaction scores corroborated these findings: the GP users reported better outcomes in terms of reducing hair damage and dryness. No significant differences in hair glossiness were observed based on the instrumental and visual assessments ( > 0.05). The safety evaluations revealed no severe adverse events. All the safety evaluation metrics demonstrated no significant abnormalities. This study provides compelling evidence of the efficacy of GP extract in enhancing hair health, demonstrating both significant functional improvements and an excellent safety profile. These findings substantiate its potential as a promising functional food ingredient for comprehensive hair care interventions.
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http://dx.doi.org/10.3390/nu17050767 | DOI Listing |
Chem Res Toxicol
September 2025
Maseeh Department of Civil, Architectural and Environmental Engineering, University of Texas at Austin, Austin, Texas 78712, United States.
Exposure to air pollution plays a significant role in human health. Current methods of measuring human exposure are often limited to outdoor measurements, are time intensive, or are unable to accurately measure certain classes of compounds. This study proposes human hair as a promising indicator of pollution exposure.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China.
Noise-induced hearing loss (NIHL), caused by irreversible cochlear hair cell (HC) damage, lacks effective therapies due to a limited understanding of endogenous protective mechanisms. The echolocating bats exhibit natural resistance to intense noise, and this suggested novel insights into methods to protect against NIHL. Here, through comparative transcriptomic analysis of noise-exposed cochleae from the eastern bent-winged bats (Miniopterus fuliginosus) and mice, the specific transcriptional dynamics in noise-resistant Miniopterus fuliginosus are revealed, thus highlighting potential mechanisms for preventing cochlear damage that mouse models cannot replicate, with Hras emerging as the most significant hub upregulator.
View Article and Find Full Text PDFInt J Vitam Nutr Res
August 2025
Department of Plastic and Cosmetic Center, The First Affiliated Hospital, Zhejiang University, 310003 Hangzhou, Zhejiang, China.
The vitamin B complex, a group of water-soluble vitamins, is essential for various metabolic and cellular processes and critical for achieving optimal surgical outcomes in plastic and cosmetic procedures. This review examines the mechanistic contributions of this complex at the cellular level, including any roles in mitochondrial bioenergetics, redox balance, gene regulation, and cellular repair mechanisms. Niacinamide, as a precursor to NAD⁺, enhances mitochondrial efficiency and facilitates energy production, supporting tissue regeneration.
View Article and Find Full Text PDFContact Dermatitis
September 2025
Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, Osnabrück, Germany.
Background: Nickel and cobalt release from tools has recently been evidenced in German hairdressing salons. Comparable data were not available for German barbershops.
Objectives: Screening of tools for nickel and cobalt release.
J Diabetes Complications
August 2025
Vrije Universiteit Brussel, Bd de la Plaine 2, 1050 Ixelles, Belgium; KidZ Health Castle, Universiteit Ziekenhuis Brussel, Av du Laerbeek 101, 1090 Jette, Belgium. Electronic address:
Aims: Our review aimed to determine the prevalence of - and factors associated with - hearing loss, oral and olfactory disease, frozen shoulder, trigger finger, and hair loss in young adults with type 1 diabetes. These conditions were selected based on research team interests, existing literature, and group discussion.
Methods: We conducted a quantitative narrative review using a systematic process to identify cohort and cross-sectional studies involving young adults with type 1 diabetes (mean age 18-30 years).