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We present a case of rosacea recurrence in a 37-year-old woman associated with the intake of compound vitamin tablets during the preconception period, with a Naranjo score of 7. These tablets, commonly used for nutritional supplementation to prevent anemia, contain a variety of vitamins, minerals, and trace elements. Despite their widespread use, reports of such supplements causing rosacea recurrence are rare. In this case, the patient experienced a recurrence of facial redness, stinging, and burning after taking the tablets on two separate occasions. Skin dermatoscopy, VISIA imaging, Clinician's Erythema Assessment (CEA), Investigator's Global Assessment (IGA), and Visual Analogue Scale (VAS) all confirmed the recurrence of rosacea. Given her intention to conceive, symptomatic treatment with emollient and reparative dressings was administered. The patient's symptoms gradually resolved after discontinuing the medication, with no recurrence observed during follow-up visits. Women with a history of rosacea should avoid these tablets during preconception, pregnancy, and lactation to prevent recurrence and should choose supplements carefully to minimize the risk of rosacea flare-ups.
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http://dx.doi.org/10.2147/JIR.S507861 | DOI Listing |
Acta Derm Venereol
September 2025
Institute of Photomedicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
COVID-19 can affect the skin, with rosacea flare-ups reported after infection or vaccination. This study compared rosacea patients with and without post-COVID-19 exacerbation to identify contributing factors. A customized electronic questionnaire was administered to rosacea patients, gathering COVID-19 infection/vaccination status, demographics, and rosacea features.
View Article and Find Full Text PDFBiochem Cell Biol
September 2025
the Second Affiliated Hospital of Hunan University of Chinese Medicine, Department of Dermatology, Changsha, Hunan, China;
Introduction: Rosacea is a chronic inflammatory skin condition marked by excessive M1 macrophage polarization and angiogenesis, resulting in erythema and tissue inflammation. Despite available treatments, many patients experience recurrent flare-ups. This study explores chelerythrine, a bioactive component of Phellodendri Chinensis Cortex, for its therapeutic potential in rosacea through modulation of NF-κB, p38 MAPK and STAT3 signaling, inflammation, and vascular regulation.
View Article and Find Full Text PDFOcul Immunol Inflamm
August 2025
Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey.
Purpose: To evaluate the clinical presentations, visual outcomes, meibography, and non-invasive tear break-up time (NIBUT) findings in pediatric ocular rosacea (OR) patients receiving maintenance therapy with topical cyclosporine.
Methods: This retrospective study reviewed medical records of patients under 16 years diagnosed with OR. Demographic characteristics, corneal involvement, delayed diagnosis, and recurrence rates were assessed.
Expert Rev Clin Pharmacol
September 2025
Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Introduction: Rosacea is a chronic skin condition classified into four subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular involvement. The physical symptoms and recurrent nature can impact patient quality of life. Effective treatment requires a phenotype-directed strategy that addresses both clinical features and patient concerns.
View Article and Find Full Text PDFCureus
July 2025
Dermatology, The Derm Institute of West Michigan, Caledonia, USA.
Lymphomatoid papulosis (LyP) is a rare cutaneous lymphoproliferative disorder involving the dysregulation of CD30-positive T-cells that accumulate in the skin. The accumulation of CD30-positive T-cells leads to the development of papulonodular lesions, which typically follow a protracted course and often resolve spontaneously in a matter of days to weeks. This case report describes a 44-year-old male patient who initially presented to the dermatology office with recurrent nodules under the right eye.
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