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In small animal practice, patients often present with urinary lithiasis, and prediction of urolith composition is essential to determine the appropriate treatment. Through abdominal radiographs, the composition of mineral radiopaque uroliths can be determined by considering many different factors; this can be complex and, as such, tailor-made for the use of artificial intelligence (AI). The Minnesota Urolith Center partnered with Hill's Pet Nutrition to develop a deep learning AI algorithm (CALCurad) within a smartphone application called the MN Urolith Application that allows for the preliminary assessment of urolith composition. The algorithm provides the probability of a urolith being composed of struvite from an image taken of an abdominal radiograph. This pilot study evaluates the accuracy of the CALCurad in the context of clinical practice. A sample population of 139 dogs was considered, and the results obtained by the CALCurad were compared with the results obtained by infrared spectroscopy analysis. Agreement between the application and quantitative analyses was 81.3%. These results suggest that the CALCurad can effectively be used to predict urolith composition in dogs, helping the clinician to decide between medical and surgical management of the patient. The use of the CALCurad is an example of the usefulness of AI in helping veterinarians make clinical decisions in patient care.
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http://dx.doi.org/10.1111/vru.70012 | DOI Listing |
Arch Esp Urol
August 2025
Department of Surgery, Hamdard Institute of Medical Sciences & Research, 110062 New Delhi, India.
Background: This study aimed to evaluate the correlation of Hounsfield unit (HU) to the success rate of medical expulsive therapy (MET) for distal ureteric calculus of size 4-10 mm.
Methods: All recruited patients were divided into two groups: Group A, who successfully passed the stone, and group B, who failed to expel the stone. All patients were prescribed with silodosin for a maximum period of 4 weeks.
Urolithiasis
September 2025
Graduate School of Engineering, The University of Osaka, 2-1, Yamadaoka, Suita, 565- 0871, Japan.
Kidney stones have a high recurrence rate-10% within 5 years and 50% within 10. Crystalluria reflects the urinary physicochemical environment and may serve as a recurrence marker, but key crystals like brushite are rarely detected under ambient conditions. This study aimed to identify novel recurrence markers by inducing crystallization through urine cooling and analyzing crystal composition.
View Article and Find Full Text PDFBMJ Open
August 2025
Department of Urology, Shanghai Pudong New Area people's Hospital, Shanghai, China
Objective: Kidney stones (KS) are a growing global health concern with significant morbidity. Although individual lifestyle factors have been linked to KS risk, the combined influence of healthy lifestyles and the mediating role of lipid metabolism remains unclear. This study aimed to investigate whether the atherogenic index of plasma (AIP) mediates the link between KS risk and a composite healthy lifestyle score.
View Article and Find Full Text PDFMetabolomics
August 2025
Department of Urology, Changhai hospital of Shanghai, Navy Medical University, Changhai road, YangPu District, Shanghai, 200433, P.R. China.
Background: Kidney stone are among the most common urologic diseases characterized with metabolic disorder. Biomarker for kidney stone detection and the metabolic variables in kidney stone development have attracted increasing attention.
Methods: To explore the metabolomic and lipidomic characteristics of plasma in patients with kidney stones, we collected plasma samples from 200 participants, including 100 kidney stone patients and 100 healthy controls.
Urolithiasis
August 2025
Department of Urology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
The composition of urinary calculi serves as a critical determinant for personalized surgical strategies; however, such compositional data are often unavailable preoperatively. This study aims to develop a machine learning-based preoperative prediction model for stone composition and evaluate its clinical utility. A retrospective cohort study design was employed to include patients with urinary calculi admitted to the Department of Urology at the Second Affiliated Hospital of Zhengzhou University from 2019 to 2024.
View Article and Find Full Text PDF