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Inspired by biological sensors that characteristically adapt to varying stimulus ranges, efficiently detecting stimulus changes sooner than the absolute stimulus values, we propose a mechanosensing concept in which the resolution can be adapted by magnetic field () gating to detect small pressure-changes under a wide range of compressive stimuli. This is realized with resistive sensing by pillared -driven assemblies of soft ferromagnetic electrically conducting particles between planar electrodes under a voltage bias. By modulation of , the pillars respond with mechanically adaptable sensitivity. Higher enhances current resolution, while it increases scatter among repeating measurements due to increased magnetic structural jamming between colloids in their assembly. To manage the trade-off between electrical resolution and scatter, machine learning is introduced for searching optimum gatings, thus facilitating efficient pressure prediction. This approach suggests bioinspired pathways for developing adaptive stimulus-responsive mechanosensors, detecting subtle changes across varying stimuli levels with enhanced effectiveness through machine learning.
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http://dx.doi.org/10.1021/acsmaterialslett.4c02021 | DOI Listing |
BMC Oral Health
September 2025
Oral and Maxillofacial Radiology Department, Cairo university, Cairo, Egypt.
Aim: The purpose of this study was to assess the accuracy of a customized deep learning model based on CNN and U-Net for detecting and segmenting the second mesiobuccal canal (MB2) of maxillary first molar teeth on cone beam computed tomography (CBCT) scans.
Methodology: CBCT scans of 37 patients were imported into 3D slicer software to crop and segment the canals of the mesiobuccal (MB) root of the maxillary first molar. The annotated data were divided into two groups: 80% for training and validation and 20% for testing.
BMC Nephrol
September 2025
School of Computer Science and Technology, Guangxi University of Science and Technology, Liuzhou, China.
BMC Psychiatry
September 2025
Department of Cognitive Neuroscience, Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Obsessive-compulsive disorder (OCD) is a chronic and disabling condition affecting approximately 3.5% of the global population, with diagnosis on average delayed by 7.1 years or often confounded with other psychiatric disorders.
View Article and Find Full Text PDFOdontology
September 2025
Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Orthodontic-induced gingival enlargement (OIGE) affects approximately 15-30% of patients undergoing orthodontic treatment and remains largely unpredictable, often relying on subjective clinical assessments made after irreversible tissue changes have occurred. S100A4 is a well-characterized marker of activated fibroblasts involved in pathological tissue remodeling. This was a cross-sectional precision biomarker study that analyzed gingival tissue samples from three groups: healthy controls (n = 60), orthodontic patients without gingival enlargement (n = 31), and patients with clinically diagnosed OIGE (n = 61).
View Article and Find Full Text PDFJ Cancer Res Clin Oncol
September 2025
Department of Surgery, Mannheim School of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Purpose: The study aims to compare the treatment recommendations generated by four leading large language models (LLMs) with those from 21 sarcoma centers' multidisciplinary tumor boards (MTBs) of the sarcoma ring trial in managing complex soft tissue sarcoma (STS) cases.
Methods: We simulated STS-MTBs using four LLMs-Llama 3.2-vison: 90b, Claude 3.