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http://dx.doi.org/10.1080/14728222.2025.2464176 | DOI Listing |
J Cosmet Dermatol
September 2025
Department of Dermatology, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, China.
Purpose: To evaluate the efficacy and underlying mechanism of advanced optimal pulse technology intense pulsed light (AOPT) in low-energy triple-pulse long-width mode (AOPT-LTL) for melasma treatment.
Methods: An in vivo guinea pig model of melasma was established through progesterone injection and ultraviolet B radiation. Three sessions of AOPT-LTL treatment were performed weekly.
BMB Rep
September 2025
Department of Microbiology, Jeonbuk National University Medical School, Jeonju 54896; Department of R&D, Cutiimunebio Inc., Jeonju 54907, Korea.
Atopic dermatitis (AD) is a chronic dermatological disorder characterized by intense pruritus and eczematous lesions. Repeated topical application of 2,4-dinitrofluorobenzene (DNFB) in NC/Nga mice produces AD-like clinical symptoms that closely resemble human AD. N-Acetyl-L-Alanine (L-NAA), a derivative of L-Alanine, has unknown biological and physiological effects on cutaneous tissue.
View Article and Find Full Text PDFJ Hazard Mater
September 2025
College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR C
Silicon dioxide nanoparticles (SiO NPs) are a novel material with a wide range of applications whose cumulative effects in the body pose certain health risks. The types of gastric injuries caused by different-sized SiO NPs and their mechanisms, however, remain unclear. Based on this, we established a mouse subchronic exposure model (10 mg/kg/d, 21 consecutive days of tube-feeding) with different SiO NP sizes (50, 300, and 1000 nm) in conjunction with in vitro MC9 and BMMCs models (160 μg/mL exposure for 24 h) to explore the gastric injury mechanisms.
View Article and Find Full Text PDFPrev Vet Med
September 2025
DNAtech, Laboratório Veterinário, Lisboa, Portugal; CECAV, Centro de Ciencia Animal e Veterinaria, Faculdade de Medicina Veterinaria, Universidade Lusofona-Centro Universitário de Lisboa, Portugal; CBIOS - Centro de Investigaçao em Biociencias e Tecnologias da Saúde - Universidade Lusofona, Lis
Mol Cell Probes
September 2025
Department of Urology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, 453100, China. Electronic address:
Background: Interleukin-1 receptor-like 1 (IL1RL1, also known as ST2) plays a critical role in immune regulation. Pan-cancer analysis has revealed that IL1RL1 is closely associated with cellular immune functions; however, its role in clear cell renal cell carcinoma (ccRCC) and the tumor microenvironment (TME) remains poorly defined.
Methods: We analyzed IL1RL1 expression patterns using data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases.