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The study aims to assess the fluence distribution and point dosage between two phantoms for patient-specific quality assurance on the Tomotherapy system. This was a retrospective study conducted on 15 patients who had radiation using the Helical Tomotherapy Machine (Radixact, Accuray Inc.). We used two phantoms to quantify the fluence produced by the treatment planning system (TPS) and recorded from the machine. The ArcCHECK (Sun-Nuclear) has 1386 diodes placed in a cylindrical configuration. The minimal resolution for this was 7 mm. The second was Delta, supplied by ScandiDos. It has 1069 diode detectors arrayed in a crossed orthogonal configuration with a minimum resolution of 5 mm. All patient plans were transferred to these phantoms to validate the accuracy of treatment plan delivery. We used SunCHECK and ScandiDos Delta software to compare the fluence produced by the TPS with the fluence measured by the equipment. In ArcCHECK, we used an external ionization chamber, cc13 (IBA dosimetry), whereas in Delta,we employed a central diode detector to quantify point dosage. The mean and standard deviation of the gamma pass percentage with ArcCHECK were 98.3 ± 0.8%, with an average point dose deviation of ± 0.94%. The mean and standard deviation of the gamma pass percentage using Delta was 99.1 ± 1.6%, while the average point dose deviation was ± 0.60%, both of which were well within the 3% tolerance employing the two phantoms.
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http://dx.doi.org/10.4103/jmp.jmp_130_24 | DOI Listing |
Overview: We analysed Australian Immunisation Register (AIR) data, predominantly for National Immunisation Program funded vaccines, as at 2 April 2023 for children, adolescents and adults, focusing on the calendar year 2022 and on trends from previous years. This report aims to provide comprehensive analysis and interpretation of vaccination coverage data to inform immunisation policy and programs.
Children: Fully vaccinated coverage in Australian children in 2022 was 0.
PLoS One
September 2025
Departamento de Biología, Escuela de Ciencias e Ingeniería, Universidad del Rosario, Bogotá, Colombia.
Honey bees (Apis mellifera) are essential pollinators threatened by sublethal effects of pesticides such as imidacloprid, a widely used neonicotinoid that disrupts the central nervous system. However, many of the systemic effects are poorly understood, especially on the physiological homeostasis of the honey bee. We evaluated the effects of oral administration of imidacloprid and the flavonol rutin on the properties of extracellular fluid (ECF) in Apis mellifera.
View Article and Find Full Text PDFUnlabelled: Passive Acoustic Mapping (PAM) is rapidly emerging as a ubiquitous tool for real-time localization and monitoring of therapeutic ultrasound treatments involving cavitation in the context of safety or efficacy. The ability of PAM to spatially quantify and resolve cavitation activity offers a unique opportunity to correlate the energy of cavitation phenomena with locally observed bioeffects.
Objective: We aim to develop methods of measuring and reporting spatio-temporally varying cavitation energies that are energy-preserving, device-independent, and adequately normalized to the volume of tissue being affected by the reported cavitation activity.
J Vet Pharmacol Ther
September 2025
Clinical Sciences Department, Colorado State University, Fort Collins, Colorado, USA.
The purpose of this study was to evaluate the pharmacokinetics of oral (PO) ondansetron compared to intravenous (IV) ondansetron in eight healthy client-owned dogs. Dogs were randomized to one of two protocols in a crossover design, receiving PO or IV ondansetron at a dose of 1 mg/kg on Day 0 and the opposite formulation at an equal dose on Day 7. Plasma was collected at baseline and 1, 2, 4, and 8 h post administration.
View Article and Find Full Text PDFJpn J Radiol
September 2025
Department of Radiology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, Jiangsu, China.
Background: Stroke, frequently associated with carotid artery disease, is evaluated using carotid computed tomography angiography (CTA). Dual-energy CTA (DE-CTA) enhances imaging quality but presents challenges in maintaining high image clarity with low-dose scans.
Objectives: To compare the image quality of 50 keV virtual monoenergetic images (VMI) generated using Deep Learning Image Reconstruction (DLIR) and Adaptive Statistical Iterative Reconstruction-V (ASIR-V) algorithms under a triple-low scanning protocol in carotid CTA.