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Purpose: To explore the healing status of interportal capsulotomies without repair after arthroscopy in patients with femoroacetabular impingement syndrome (FAIS) and to examine its correlation with clinical outcomes, including the relationship with age and sex subgroups.
Methods: Data collected between August 2015 and January 2022 were reviewed. Patients with FAIS aged 18 to 65 years who underwent hip arthroscopy with interportal capsulotomies without repair with a minimum 2-year follow-up were included. Patients with a lateral center-edge angle of less than 25°, Tönnis grade greater than 1, Perthes disease, slipped upper femoral epiphysis, avascular necrosis, prior ipsilateral hip injury or surgery, and absence of magnetic resonance imaging at final follow-up were excluded. Patients were divided into healed and unhealed capsule groups according to magnetic resonance imaging evaluation. The primary patient-reported outcome (PRO) was the modified Harris Hip Score (mHHS). The secondary PROs were the Hip Outcome Score-Activities of Daily Living subscale, Hip Outcome Score-Sport Specific subscale, University of California at Los Angeles score, and visual analog scale pain score at final follow-up. The percentages of patients achieving the minimal clinically important difference (MCID) and patient acceptable symptom state (PASS) for the PROs were also calculated.
Results: The cohort comprised 69 patients (72 hips), with 28 hips (38.89%) in the unhealed capsule group and 44 hips (61.11%) in the healed capsule group. The cohort comprised 32 male and 37 female patients, and the mean age of the patients was 44.15 years. Within each group, there were significant preoperative-to-postoperative increases in the mHHS, Hip Outcome Score-Activities of Daily Living, Hip Outcome Score-Sport Specific subscale, and University of California at Los Angeles score and decreases in the visual analog scale pain score (all P < .001). There were no significant differences between the healed and unhealed groups in the PROs and the achievement rates of the MCID and PASS (all P > .05). In addition, compared with the healed group, the unhealed group showed worse mHHS values in patients older than 40 years (P = .003) and female patients (P = .036) on subgroup analysis by age and sex, respectively.
Conclusions: At a minimum 2-year follow-up, 38.89% of patients with FAIS who underwent arthroscopic surgery with interportal capsulotomy without repair had unhealed hip capsules. There were no significant differences in PROs or achievement rates of the MCID and PASS between the healed and unhealed groups. Subgroup analysis showed that age older than 40 years and female sex may be associated with worse efficacy in patients with unhealed capsules.
Level Of Evidence: Level III, retrospective case-control study.
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http://dx.doi.org/10.1016/j.arthro.2025.01.035 | DOI Listing |
Front Pharmacol
August 2025
Department of Anorectal Medicine, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, China.
Background: Calcium channel blockers (CCBs) are first-line pharmacotherapy for chronic anal fissures (CAF), but the optimal administration route (oral vs. topical) remains unclear. This systematic review and meta-analysis compared efficacy and safety of oral vs.
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December 2025
Histology and Cell Biology Department, Faculty of Medicine, Suez University, Suez, Egypt.
Background: Diabetic foot ulcers (DFUs) are a serious complication of diabetes that can lead to significant morbidity. Autologous platelet-rich plasma (PRP), rich in growth factors and cytokines, has emerged as a promising treatment to enhance ulcer healing. This study aimed to compare the clinical and histological efficacy of injected PRP versus topically applied PRP and traditional wound care in the management of DFUs.
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MA BSc (Hons) DpSN RGN, Tissue Viability Consultant and Lymphoedema Nurse, Wound Care Consultants Ltd.
Mr H, an 85-year-old man, had undergone a heart bypass surgery 10 years ago and had been living with non-healing a leg ulcer for 9 years. He was also one of the first members of the Leg Club. With a fourlayer compression bandaging, regular wound cleansing with non-cytotoxic solutions, and application of primary dressings tailored to exudate levels, Mr H's leg ulcer healed within 8 weeks, much sooner than the expected 12-week period.
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May 2025
Northern Regional Burn Centre, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
Introduction: Accurate burn wound assessment is essential for effective treatment, yet it remains heavily dependent on clinical judgment, which is highly subjective. While various optical-based instruments have been developed to address this issue, their clinical effectiveness has been limited due to high cost, penetration depth, lack of portability and validation primarily for use on days 2-5 post injury. The integration of artificial intelligence (AI) with multispectral imaging (MSI) represents a potential advancement in enhancing the accuracy and consistency of wound assessment.
View Article and Find Full Text PDFBiomaterials
August 2025
Department of Wound healing, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015, China; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health), National Key Laboratory of Macromolecular Drugs and Large-scale Preparation, School of Pharmaceutic
Patients with diabetes often exhibit delayed wound healing, which is characterized by the endothelial cells dysfunction and excessive accumulation of free tissue iron. Ferroptosis, a form of regulated cell death driven by iron-dependent lipid peroxidation, has been implicated in the pathogenesis of diabetic complications, though its role in angiogenesis under hyperglycemia remains unknown. In this study, we revealed a distinct ferroptosis-associated metabolic phenotype in endothelial cells derived from unhealed diabetic foot ulcers (DFUs) and under high glucose exposure in vitro, marked by elevated intracellular reactive oxygen species (ROS) levels and impaired mitochondrial function.
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