Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786514PMC
http://dx.doi.org/10.1186/s12866-025-03787-xDOI Listing

Publication Analysis

Top Keywords

correction antimicrobial
4
antimicrobial resistance
4
resistance virulence
4
virulence gene
4
gene profiling
4
profiling genetic
4
genetic diversity
4
diversity multidrug-resistant
4
multidrug-resistant pseudomonas
4
pseudomonas aeruginosa
4

Similar Publications

Objectives: This study focused on synthesizing and characterizing novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety and evaluating their antimicrobial activity against several bacterial strains. The research aimed to identify key structural features that enhance antimicrobial efficacy through structure-activity relationship analysis and identify the minimum inhibitory concentration (MIC) of the most potent compounds to assess their potential for further development as antimicrobial agents.

Materials And Methods: Nine novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety were synthesized by reacting 1,2,4-triazole derivatives with thiosemicarbazide precursors, and the products were characterized using infrared spectroscopy, proton nuclear magnetic resonance (H-NMR), carbon-13 nuclear magnetic resonance (C-NMR) spectroscopy, and elemental analysis.

View Article and Find Full Text PDF

Objective: To evaluate the quality of care provided to patients with febrile neutropenia (FN) hospitalized at the Depart-ment of Infectious Diseases, Military University Hospital Prague, as a foundation for improving the management of this condition.

Material And Methods: A retrospective observational analysis of patients diagnosed with the ICD-10 code D70 from 1 January 2015 to 1 June 2023. All evaluated parameters were selected primarily to facilitate the assessment of care quality and compliance with recommended practices.

View Article and Find Full Text PDF

Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) Study: A randomized, double-masked, sham-controlled clinical trial of rose bengal photodynamic therapy.

Ophthalmology

September 2025

Francis I. Proctor Foundation, University of California San Francisco, USA; UCSF Department of Ophthalmology, University of California, San Francisco, USA; Byers Eye Institute, Stanford University, Palo Alto, USA. Electronic address:

Objective: To determine the effect of adjunctive rose-bengal photodynamic therapy (RB-PDT) in the treatment of fungal, Acanthamoeba, and smear/culture negative infectious keratitis.

Study Design: This international, randomized, double-masked, sham controlled clinical trial, randomizes patients with corneal ulcers in a 1:1 fashion to one of two treatment arms: 1) Topical antimicrobial plus sham RB-PDT or 2) Topical antimicrobial plus RB-PDT.

Main Outcome Measures: The primary outcome was best spectacle-corrected visual acuity (BSCVA) at 6 months.

View Article and Find Full Text PDF

Background And Aims: Large language models (LLMs) can potentially support clinicians in their daily routine by providing easy access to information. Yet, they are plagued by stating incorrect facts and hallucinating when queried. Increasing the context by providing external databases while prompting LLMs may decrease the risk of misinformation.

View Article and Find Full Text PDF