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http://dx.doi.org/10.7554/eLife.105985 | DOI Listing |
Case Rep Pediatr
September 2025
Department of Thoracic Surgery, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.
Ectopia cordis is an exceptionally uncommon congenital condition where the heart develops outside its normal position due to incomplete closure of the ventral chest wall during embryogenesis. The anomaly may occur in isolation or with other structural defects, often resulting in a poor prognosis despite advancements in medical and surgical care. This report discusses a preterm neonate delivered at 33 weeks of gestation following an uneventful pregnancy in a dizygotic twin gestation.
View Article and Find Full Text PDFClin Kidney J
September 2025
Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.
Genome editing technologies, particularly clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9, have transformed biomedical research by enabling precise genetic modifications. Due to its efficiency, cost-effectiveness and versatility, CRISPR has been widely applied across various stages of research, from fundamental biological investigations in preclinical models to potential therapeutic interventions. In nephrology, CRISPR represents a groundbreaking tool for elucidating the molecular mechanisms underlying kidney diseases and developing innovative therapeutic approaches.
View Article and Find Full Text PDFFront Cell Infect Microbiol
August 2025
Department of Anorectal, Tianjin Union Medical Center The First Affiliated Hospital of Nankai University, Tianjin, China.
[This corrects the article DOI: 10.3389/fcimb.2025.
View Article and Find Full Text PDFClin Ophthalmol
September 2025
Università degli studi di Milano, Milan, Italy.
Purpose: To report clinical outcomes in patients implanted with an isofocal optic-design intraocular lens (IOL) with double C-loop haptics following cataract surgery.
Methods: This was a multicentre-prospective-study involving 108 eyes (54 subjects) implanted with the Isopure Serenity (BVI, Inc). IOL.
Cureus
August 2025
Physiology, SGT University, Gurugram, IND.
Introduction Simulation-based training has been a vital part of medical education since Competency-Based Medical Education (CBME) was introduced, and new guidelines since 2023 have expanded to include simulation as a mandatory methodology of teaching. This method enables learners to build and develop both technical and non-technical abilities in a safe and controlled setting, enhancing their preparedness for real-life medical scenarios. Simulation-based training improves skill acquisition and retention and enhances learners' confidence, reduces anxiety, reinforces learning, corrects errors, and promotes reflective practice, in contrast with the traditional method of teaching.
View Article and Find Full Text PDF