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Optical edge detection is a crucial optical analog computing method in fundamental artificial intelligence, machine vision, and image recognition, owing to its advantages of parallel processing, high computing speed, and low energy consumption. Field-of-view-tunable edge detection is particularly significant for detecting a broader range of objects, enhancing both practicality and flexibility. In this work, a novel approach-adaptive optical spatial differentiation is proposed for field-of-view-tunable edge detection. This method improves the ability to acquire spatial information and facilitates edge detection over a wider angular range. The adaptive optical spatial differentiation meta-device relies on two core components: the spatial differentiation dielectric metasurface and the adaptive liquid prism. The meta-device is shown to function as a highly efficient (≈85%) isotropic spatial differentiator, operating across the entire visible spectrum (400 to 700 nm) within a wide-angle object space, expanding up to 4.5 times the original field of view. The proposed scheme presents new opportunities for efficient, flexible, high-capacity integrated data processing and imaging devices. And simultaneously provides a novel optical analog computing architecture for the next generation of wide field-of-view phase contrast microscopy.
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http://dx.doi.org/10.1002/advs.202412794 | DOI Listing |
Cell Syst
September 2025
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:
Spatial transcriptomics allows for the measurement of gene expression within the native tissue context. However, despite technological advancements, computational methods to link cell states with their microenvironment and compare these relationships across samples and conditions remain limited. To address this, we introduce Tissue Motif-Based Spatial Inference across Conditions (TissueMosaic), a self-supervised convolutional neural network designed to discover and represent tissue architectural motifs from multi-sample spatial transcriptomic datasets.
View Article and Find Full Text PDFChemosphere
September 2025
UMR Epoc 5805, Bordeaux-INP. 1 Allée Daguin, 33607, Pessac cedex, France. Electronic address:
In order to validate some assumptions and calculations of Johnson and Ettinger's model, a mapping of measured VOC fluxes in a heavily contaminated building was undertaken. To this end, both advective and diffusive flux measurements were carried out under real conditions. Diffusive fluxes were measured with flux chambers recording the initial concentration rise during the first minutes.
View Article and Find Full Text PDFWater Res
September 2025
College of Hydrology and Water Resources, Hohai University, Nanjing 210098, China. Electronic address:
Groundwater overextraction presents persistent challenges due to strategic interdependence among decentralized users. While game-theoretic models have advanced the analysis of individual incentives and collective outcomes, most frameworks assume fully rational agents and neglect the role of cognitive and social factors. This study proposes a coupled model that integrates opinion dynamics with a differential game of groundwater extraction, capturing the interaction between institutional authority and evolving stakeholder preferences.
View Article and Find Full Text PDFPLoS One
September 2025
Biaoxin Science & Technology (Beijing) Co., Ltd, Beijing, China.
This study examines China's national standard development from 2001 to 2023. Using machine splitting and location assignment technology, the Dagum Gini coefficient and its decomposition methods, and traditional and spatial Markov chain estimation methods, we identify the spatiotemporal disparities and dynamic transition characteristics of the contribution levels to national standard development across China's eight comprehensive economic zones. The findings provide a reference for promoting regional coordinated sustainable development and high-quality economic transformation.
View Article and Find Full Text PDFBioinformatics
September 2025
Department of Mathematical Sciences, The University of Texas at Dallas, TX United States.
Motivation: The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context. Understanding gene functions and interactions in different spatial domains is crucial, as it can enhance our comprehension of biological mechanisms, such as cancer-immune interactions and cell differentiation in various regions. It is necessary to cluster tissue regions into distinct spatial domains and identify discriminating genes that elucidate the clustering result, referred to as spatial domain-specific discriminating genes (DGs).
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