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Background: Cultured meat technology represents an innovative food production approach that enables the large-scale cultivation of animal cells to obtain muscle, fat, and other tissues, which are then processed into meat products. Compared with traditional meat production methods, cell-cultured meat may significantly reduce energy consumption by 7%-45%, greenhouse gas emissions by 78%-96%, land use by 99%, and water use by 82%-96%. This technology offers several advantages, including a shorter production cycle and enhanced environmental sustainability, resource efficiency, and overall sustainability. However, numerous technical challenges remain.
Objectives: The latest advancements in cultured meat research were reviewed such as the development of serum-free media, maintenance of seed cell functionality, large-scale cell culture techniques, 3-dimensional culture methods, and innovations in scaffold materials.
Methods: Recent publications on cultured meat were examined.
Results: These hurdles were addressed to achieve low-cost, high-efficiency industrial production in the cultivated meat sector. Furthermore, as a supplement or substitute for traditional meat, cultured meat products must possess similar sensory characteristics and nutritional value, ensure high food safety standards, and maintain low production costs to enhance market competitiveness.
Conclusions: Achieving the industrialization of cultured meat necessitates careful consideration of several additional challenges related to sensory attributes, nutritional quality, food safety, and consumer acceptance. This review systematically examines these aspects to provide a theoretical and practical foundation for the sustainable biomanufacturing of cultured meat.
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http://dx.doi.org/10.1016/j.tjnut.2025.01.010 | DOI Listing |
Food Chem
September 2025
State Key Laboratory of Meat Quality Control and Cultured Meat Development; Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:
At moderate protein concentrations (10, 20 mg/mL) and a high temperature (80 °C), meat protein (MP) self-assembled into weak gels and then intriguingly collapsed into microgels through continuous heating and annealing cooling, resulting in a sol state with exposed hydrophobic groups and disulfide bonds. The different prepared microgel groups were labeled as MP and MP, respectively. Compared with the control group (Con: 7.
View Article and Find Full Text PDFFood Res Int
November 2025
College of Animal Sciences, Zhejiang University, Hangzhou, China; Key Laboratory of Molecular Animal Nutrition (Zhejiang University), Ministry of Education, China. Electronic address:
Cultured meat is an emerging field in future food production, employing interdisciplinary strategies that integrate the food industry, tissue engineering, and biotechnology to meet global food needs. Cultivating meat from stem cells is an increasingly recognized solution to address concerns associated with animal husbandry in terms of environment, health, and ethics. Despite significant advances, substantial technical challenges persist.
View Article and Find Full Text PDFFood Res Int
November 2025
College of Food Science, Southwest University, Chongqing 400715, China. Electronic address:
Cultured meat represents an innovative alternative to conventional livestock-derived meat, yet faces challenges in establishing efficient, safe, and sustainable culture systems. Although traditional supplements such as fetal bovine serum and bovine eye fluid provide essential growth factors for cell proliferation, their high cost, ethical concerns, and biosafety risks significantly hinder large-scale industrialization. In recent years, protein hydrolysates have emerged as promising components in serum-free media.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Institute of Postharvest and Food Sciences, Agricultural Research Organization (ARO), Volcani Center, 68 HaMaccabim Road, Rishon Letzion 7505101, Israel.
Cultivating fat for edible tissue presents significant challenges, due to the high costs associated with growth and differentiation factors, alongside the poor viability of adipocytes resulting from cell clustering. Additionally, there is a gap in research regarding the rapid accumulation of fats within cells. To that end, this study presents the development of a biodegradable soy protein colloidosome system for an efficient application: direct delivery of oils into bovine satellite cells, enabling rapid intracellular fat accumulation without the need for adipogenic differentiation.
View Article and Find Full Text PDFFood Chem
September 2025
Jiaxing Institute of Future Food, Jiaxing 314050, China; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. Electronic address:
This paper aims to explore the feasibility of enhancing the printing performance of 3D-printed meat analogues by varying the substitution amount of camellia seed cake protein (SCP) in the edible ink system based on proteins and polysaccharides. It covers the ink formulation, rheological properties and product analysis. The addition of SCP can significantly enhance the apparent viscosity, mechanical strength, and water retention capacity of the inks.
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