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Mesothelial cysts in the uterus are exceedingly rare. A 41-year-old patient presented with complaints of abdominal pain, and transvaginal ultrasonography revealed an enlarged uterus with a hypoechoic intramural cystic mass measuring 7.2 × 3.3 × 3.6 cm in the posterior uterine corpus. Suspecting a degenerated leiomyoma, the patient underwent a total laparoscopic hysterectomy and bilateral salpingectomy. Intraoperatively, a cystic lesion approximately 7 cm in size was observed within the myometrium of the posterior uterine wall. Pathological examination, supported by immunohistochemical findings, confirmed the diagnosis of a mesothelial cyst. Mesothelial cysts can mimic various clinical and radiological entities, and definitive diagnosis is typically established through pathological evaluation following complete excision of the lesion.
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http://dx.doi.org/10.7759/cureus.75158 | DOI Listing |
Zhonghua Bing Li Xue Za Zhi
September 2025
Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao 266000, China.
To investigate the clinicopathological characteristics of well-differentiated papillary mesothelial tumor (WDPMT). Sixteen cases of resected WDPMTs diagnosed at the Affiliated Hospital of Qingdao University, Qingdao, China from 2017 to 2024 were collected and the clinicopathological features were retrospectively analyzed. There were 7 males amd 9 females, with a mean age of 53.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York City, NY, United States.
Introduction: Thoracic SMARCA4-deficient undifferentiated tumor (SMARCA4-dUT) is a recently described type of lung cancer, presenting as a bulky mass variably involving the mediastinum and the lung in patients with smoking history, and exhibits adverse prognosis. The essential diagnostic immunomorphologic features and typical genomic findings have been described. However, there is a continuing need to catalogue the spectrum of genomic changes underlying the disease, the heterogeneity of antigen expression in order to avoid diagnostic pitfalls, and any variability in patient outcomes.
View Article and Find Full Text PDFCell Death Dis
August 2025
Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in pro-inflammatory conditions, including peritoneal dialysis (PD), a renal replacement therapy. Characteristic of this process is the acquisition of invasive/pro-fibrotic abilities by mesothelial cells (MCs) through induction of mesothelial to mesenchymal transition (MMT), a cell-specific form of EMT. Long noncoding (lnc) RNAs act as major players in physiologic regulatory circuitries of the cell.
View Article and Find Full Text PDFCommun Biol
August 2025
Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Platinum-resistant ovarian cancer (PROC) is a clinically severe unresolved issue, and it remains unclearly defined by molecular biology. Extracellular vesicles (EVs) play an essential role in cell-to-cell communication in the tumor microenvironment. This study aimed to investigate the molecular mechanisms of PROC, focusing on the unique ascites environment of ovarian cancer.
View Article and Find Full Text PDFAnimals (Basel)
August 2025
Hubei Key Laboratory of Animal Nutrition and Feed Science, School of Animal Science and Nutritional Engineering, Wuhan Polytechnic University, Wuhan 430023, China.
() is a Gram-negative, pathogenic bacterium that colonizes the upper respiratory tract of piglets and causes Glässer's disease with peritonitis under stress conditions. The mechanism underlying GPS-induced peritonitis in piglets remains unclear. Baicalin is one of the main active ingredients of Huangqin (), which has a significant anti-inflammatory effect on inflammatory diseases.
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