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We investigated the distribution and antimicrobial resistance of 120 Staphylococcus felis isolates from feline patients in Japan, mainly from the urinary tract (28.3%), abscesses (23.3%), ears (22.5%), and nasal cavity (10.8%). The distribution of S. felis differed from those of previous studies in Japan and other countries. Antimicrobial susceptibility testing revealed a relatively high resistance to penicillin (PEN, 33.3%), followed by erythromycin (ERY, 15.8%), clindamycin (CLI, 13.3%), and levofloxacin (5.0%). However, oxacillin resistance was not detected. Notably, 11/120 (9.2%)S. felis isolates exhibited multidrug resistance, i.e., resistance to more than three classes of drugs, which mainly consisted of PEN-ERY-CLI resistance phenotypes. This is the first investigation on antimicrobial-resistant S. felis isolates from feline patients in Japan.
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http://dx.doi.org/10.1292/jvms.24-0452 | DOI Listing |
Klin Mikrobiol Infekc Lek
June 2025
Institute of Infectious Diseases and Microbiology, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno,Czech Republic, e-mail:
Capnocytophaga spp. are typical members of the commensal microflora of the oral cavity. However, C.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2025
State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, China.
() is a major causative agent of feline viral rhinotracheitis and ocular lesions. Due to its large DNA genome, the construction of recombinant viruses presents considerable challenges for conventional methodologies. In this study, we implemented an integrated strategy combining CRISPR/Cas9-mediated gene editing with fluorescence-activated cell sorting (FACS) to enable the rapid and efficient generation of recombinant viruses.
View Article and Find Full Text PDFVet Med Sci
September 2025
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam Nation University, Gwangju, South Korea.
Background: Cryptococcosis is the most common systemic fungal infection in cats, typically presenting with respiratory or neurological signs. However, cases without these hallmark symptoms are rare and often misdiagnosed. This case is noteworthy for its atypical presentation, where a cat developed systemic cryptococcosis without the typical respiratory or neurological involvement, making it particularly challenging to diagnose.
View Article and Find Full Text PDFMicrob Genom
September 2025
UCL Centre for Clinical Microbiology, University College London, London, UK.
There are currently no standardized guidelines for genomic surveillance of One Health antimicrobial resistance (AMR). This project aimed to utilize metagenomics to identify AMR genes present in a companion animal hospital and compare these with phenotypic results from bacterial isolates from clinical specimens from the same veterinary hospital. Samples were collected from sites within a primary care companion animal veterinary hospital in London, UK.
View Article and Find Full Text PDFThis study evaluated a lateral flow dermatophyte antigen kit (Kit) for rapid diagnosis of feline dermatophytosis. The Kit, originally used for human onychomycosis, was tested on 20 healthy cats and six cats with dermatophytosis. Hair samples from healthy cats yielded negative Kit results, although fungal culture detected environmental fungi in 4 of 20 cases.
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