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Introduction: The Mobi-C Cervical Disc Replacement is a motion preserving alternative to anterior cervical discectomy and fusion in properly indicated patients. In 2013, Mobi-C became the first cervical disc in the United States approved to treat more than one level of the cervical spine. The FDA determined Mobi-C to be statistically superior to fusion at two levels, based on the primary endpoint of a prospective, concurrently controlled and randomized multicenter clinical trial.
Areas Covered: The history of Mobi-C and cervical disc arthroplasty is discussed. The unique biomechanics and structure of Mobi-C, the clinical results, the long term follow-up, the disc's biomechanics, and cost-effectiveness research are described. The competitive landscape is overviewed.
Expert Opinion: The evidence in this article supports the use of the Mobi-C cervical disc prosthesis as a viable alternative to fusion surgery in selected patients. Mobi-C has a relatively long track record compared to most other cervical disc prostheses. Thus far, Mobi-C is a very good option for preserving cervical motion based on long term follow-up, for achieving favorable clinical outcomes, and for maintaining patient safety. The Mobi-C cervical disc prosthesis is generally viewed positively, supported by clinical experience and research findings.
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http://dx.doi.org/10.1080/17434440.2024.2449504 | DOI Listing |
J Neurol Surg A Cent Eur Neurosurg
September 2025
Neurosurgery, InnKlinikum gkU Altötting und Mühldorf, Altötting, Germany.
Purpose: This study aimed to evaluate clinical and radiological outcomes of patients who underwent anterior cervical discectomy and fusion (ACDF) without additional anterior plate fixation.
Methods: A retrospective single-center analysis was conducted. Clinical outcomes were assessed by the Visual Analog Scale (VAS) scores, Neck Disability Index (NDI), and Odom's criteria.
Medicine (Baltimore)
September 2025
The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China.
Background: As a minimally invasive technique, Fu's subcutaneous needling (FSN) has been widely adopted in Chinese clinical practice for managing neck-type cervical spondylosis (CS). However, current evidence regarding its therapeutic efficacy remains inconclusive due to methodological limitations in existing studies. This systematic review and meta-analysis therefore sought to quantitatively synthesize available randomized controlled trials to evaluate the clinical effectiveness and safety of FSN for this prevalent musculoskeletal disorder.
View Article and Find Full Text PDFCureus
August 2025
Department of Neurosurgery, Virginia Commonwealth University, Richmond, USA.
Background Anterior cervical discectomy and fusion (ACDF) is a common surgical procedure that patients undergo for cervical disc herniations and degenerative disc disease, aimed at relieving radicular symptoms and restoring cervical alignment. The impact of preoperative kyphotic cervical imbalance versus preoperative lordosis on postoperative radiographic outcomes in ACDF patients is unclear. The purpose of this study is to examine how preoperative cervical sagittal balance can influence quantified postoperative cervical sagittal balance.
View Article and Find Full Text PDFCureus
August 2025
Musculoskeletal Sciences, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth, Krishna Institute of Medical Sciences Deemed To Be University (KIMSDU), Karad, IND.
Background: Cervical derangement syndrome (CDS), a form of mechanical neck pain, arises from poor posture, repetitive stress, and segmental dysfunction, resulting in discomfort, restricted cervical mobility, and reduced functional capacity. The study focuses on changes associated with CDS, particularly range of motion (ROM), pain, and functional disability. The study aims to find the effect of kinetic control training (KCT) and the McKenzie approach on CDS.
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Department of Neurosurgery, Independent Public Specialist Western Hospital John Paul II in Grodzisk Mazowiecki, Daleka 11, 05-825, Grodzisk Mazowiecki, PL. Electronic address:
Introduction: Anterior cervical discectomy and fusion (ACDF) is a common surgical procedure used to treat herniated discs, degenerative disc disease, and nerve root compression in the cervical spine. This systematic literature review aims to analyze the available literature on the incidence, risk factors, clinical considerations, and available therapies for spinal epidural hematoma (SEH) following ACDF.
Methods: A systematic search was conducted in PubMed, Google Scholar, and Embase from database inception to June 18, 2025, following the PRISMA guidelines.