Application of autophagy in mesenchymal stem cells.

World J Stem Cells

Department of Emergency Medicine, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China.

Published: December 2024


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Article Abstract

In this editorial, we have taken an in-depth look at the article published by Wan . The study showed that preconditioning mesenchymal stem cells (MSCs) protected them against programmed cell death, and increased their survival rate and therapeutic potential. Autophagy, a type of programmed cell death, is a major intracellular degradation and recycling pathway that is crucial for maintaining cellular homeostasis, self-renewal, and pluripotency. We have explored the relationship between autophagy and MSCs to determine the role of autophagy in the therapeutic applications of MSCs.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11669988PMC
http://dx.doi.org/10.4252/wjsc.v16.i12.990DOI Listing

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