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http://dx.doi.org/10.1111/apt.18452 | DOI Listing |
World J Diabetes
July 2025
Worker's Care & Digital Health Lab, Department of Future Technology, Korea University of Technology and Education, Cheonan 31253, South Korea.
Bariatric surgery significantly improves glycemic control and can lead to type 2 diabetes remission. However, the reliability of glycated hemoglobin (HbA1c) as a type 2 diabetes biomarker post-surgery can be confounded by conditions such as anemia and gastrointestinal complications. Hence, we explored the use of alternative biomarkers such as glycated albumin (GA), 1,5-anhydroglucitol (1,5-AG), and insulin-like growth factor binding protein-1 (IGFBP-1) to monitor glycemic control more effectively in post-bariatric surgery patients.
View Article and Find Full Text PDFIn Vitro Cell Dev Biol Anim
August 2025
Department of Cardiovascular, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Changsha, 410006, Hunan, China.
Ginsenoside Rb1 ameliorates renal fibrosis, yet its effects on myocardial fibrosis (MF) remain unclear. In this study, we aimed to explore the role of ginsenoside Rb1 in chronic heart failure (CHF) and MF. To explore the correlation between endothelial-mesenchymal transition (EndMT) in endothelial cells and IGFBP2 expression in M1 macrophages, M1 macrophages were polarized and co-cultured with myocardial microvascular endothelial cells (MMVECs).
View Article and Find Full Text PDFAdv Gerontol
June 2025
Institute of Experimental Medicine, 12 Akademik Pavlov str., St. Petersburg 197022, Russin Federation.
Physical activity plays an important role in maintaining health and slowing down aging, reducing the risk of developing a number of chronic diseases. Epidemiological data confirm a close relationship between physical activity and life expectancy. The mechanisms underlying these improvements are very complex and completely unknown.
View Article and Find Full Text PDFJ Nutr Health Aging
August 2025
State Key Laboratory of Multi-organ Injury Prevention and Treatment, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, Guangdong, China. Electronic address:
World J Gastroenterol
June 2025
The First School of Clinical Medicine, Yunnan University of Chinese Medicine, Kunming 650000, Yunnan Province, China.
Hepatocellular carcinoma (HCC) is a highly lethal malignancy with limited treatment options, particularly for patients with advanced stages of the disease. Sorafenib, the standard first-line therapy, faces significant challenges due to the development of drug resistance. Yu explored the mechanisms by which lncRNA KIF9-AS1 regulates the stemness and sorafenib resistance in HCC using a combination of cell culture, transfection, RNA immunoprecipitation, co-immunoprecipitation, and xenograft tumor models.
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