Theoretical and experimental study on a fast proton transport pathway in CeO-coated SrTiO through surface vacancy engineering for low-temperature ceramic fuel cells.

Overcoming the high-temperature limitations of ceramic fuel cells (CFCs) requires the development of electrolytes capable of efficient proton transport at reduced operating temperatures. In this work, we introduced a surface-engineered SrTiO electrolyte coated with 10 mol%-CeO, forming a core-shell heterostructure that promoted the formation of oxygen vacancies localized at the interface. These vacancies significantly reduced the energy barrier for proton migration, enabling enhanced ionic conductivity at low operating temperatures.

Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS).

Probabilistic spatial modelling techniques developed on large-scale tumor-immune Atlases (~35M individually mapped cells; 50,000 high power fields) were used to characterize predictive features of treatment-responsive lung cancer. We identified CD8+FoxP3+ cell density as a robust pre-treatment biomarker for outcomes across disease stages and therapy types. In parallel, single-cell RNAseq studies of CD8+FoxP3+ T-cells revealed an activated, early effector phenotype, substantiating an anti-tumor role, and contrasting with CD4+FoxP3+ T-regulatory cells.

First karyotype description of (Duméril, 1861) with comments on chromosome evolution in the genus Gill, 1862 (Nothobranchiidae).

The African non-annual killifish genus Gill, 1862 (family Nothobranchiidae) comprises 36 valid species distributed in West, Central and East Africa. The available cytogenetic information for the genus indicates a wide variability in diploid chromosome number (2n) and number of chromosome arms (FN). Here, we report the karyotype of (Duméril, 1861), one of the two species with the lowest diploid chromosome number (2n = 34) in the genus, from the White Nile basin in Ethiopia.

[Patterns of physiological reactions to standardized cardiorespiratory load as markers of age-related changes.].

The aging process is associated with a decrease in cardiorespiratory endurance. The profile of changes in hemodynamic parameters, respiratory and metabolic profile during cardiopulmonary exercise testing in the elderly can identify patients with subclinical forms of diseases. It is necessary to develop a standardized approach to the interpretation of parameters that can serve as diagnostic signs of an abnormal response of physiological parameters to physical activity and have optimal prognostic and differential diagnostic value.

[The effect of physical activity on biomarkers of aging in normal and pathological conditions (analytical review).].

Physical activity plays an important role in maintaining health and slowing down aging, reducing the risk of developing a number of chronic diseases. Epidemiological data confirm a close relationship between physical activity and life expectancy. The mechanisms underlying these improvements are very complex and completely unknown.