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Article Abstract

Dear Editor, in this study, we propose a novel linkage disequilibrium information-based noninvasive zygosity (LDNZ) assessment method in twin pregnancies. It combines fetus-specific allele frequency analysis with LD block to reduce the number of required single nucleotide polymorphism markers and experiment costs. LDNZ method offers a noninvasive, accurate, and cost-effective solution for zygosity assessment, addressing the need for precise obstetric care in twin pregnancies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659192PMC
http://dx.doi.org/10.1002/ctm2.70130DOI Listing

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