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In the face of growing health challenges, nontraditional sources of data, such as open data, have the potential to transform how decisions are made and used to inform public health policies. Focusing on the COVID-19 pandemic, this article presents a case study employing sentiment analysis on unstructured social media data from Twitter (now X) to gauge public sentiment regarding pandemic-related restrictions. Our study aims to uncover and analyze Jamaican citizens' emotions and opinions surrounding COVID-19 restrictions following an outbreak at a call center in April 2020. Machine learning sentiment analysis was used to analyze tweets from Twitter related to the lockdown. A total of 1 609 tweets were retrieved and analyzed, 76% of which expressed negative sentiments, suggesting that the majority of citizens were not in favor of the restrictions. The low compliance with the government-mandated policy may be related to the high percentage of negative sentiments expressed. Insights from citizens' sentiments derived from open data sources such as Twitter can serve as valuable indicators for public health policymakers, providing critical input that will aid in tailoring interventions that align with public sentiments, thereby enhancing the effectiveness of and compliance with public health policies. This type of analysis can be useful to the health community and more generally to governments, as it allows for a more scientific assessment of public response to public health intervention techniques in real time. This study contributes to the emerging discourse on the integration of nontraditional data into public health policy-making, highlighting the growing potential for the use of these novel analytic techniques in addressing complex public health challenges.
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http://dx.doi.org/10.26633/RPSP.2024.79 | DOI Listing |
Mutat Res Rev Mutat Res
September 2025
Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address:
To maintain genomic stability, cells have evolved complex mechanisms collectively known as the DNA damage response (DDR), which includes DNA repair, cell cycle checkpoints, apoptosis, and gene expression regulation. Recent studies have revealed that long non-coding RNAs (lncRNAs) are pivotal regulators of the DDR. Beyond their established roles in recruiting repair proteins and modulating gene expression, emerging evidence highlights two particularly intriguing functions.
View Article and Find Full Text PDFJ Trace Elem Med Biol
September 2025
Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. Electronic address:
Objective: We previously documented that exposure to a spectrum of elements is associated with autism spectrum disorder (ASD). However, there is a lack of mechanistic understanding as to how elemental mixtures contribute to the ASD development.
Materials And Methods: Serum and urinary concentrations of 26 elements and six biomarkers of ASD-relevant pathophysiologic pathways including serum HIPK 2, serum p53 protein, urine malondialdehyde (MDA), urine 8-OHdG, serum melatonin, and urine carnitine, were measured in 21 ASD cases and 21 age-matched healthy controls of children aged 6-12 years.
J Crit Care
September 2025
Neuro-Intensive Care Unit, Department of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China; Neuro-intensive Care Unit, Department of Neurosurgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China. Electronic address:
J Crit Care
September 2025
Neuro-Intensive Care Unit, Department of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China; Neuro-intensive Care Unit, Department of Neurosurgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China. Electronic address:
Int J Epidemiol
August 2025
Department of Biostatistics and Informatics, University of Colorado, Aurora, CO, United States.
Background: Existing longitudinal cohort study data and associated biospecimen libraries provide abundant opportunities to efficiently examine new hypotheses through retrospective specimen testing. Outcome-dependent sampling (ODS) methods offer a powerful alternative to random sampling when testing all available specimens is not feasible or biospecimen preservation is desired. For repeated binary outcomes, a common ODS approach is to extend the case-control framework to the longitudinal setting.
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