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To enhance the efficiency of machine vision system, physical hardware capable of sensing and encoding is essential. However, sensing and encoding color information has been overlooked. Therefore, this work utilizes an indium-gallium-zinc oxide (IGZO) phototransistor to detect varying densities of red, green, and blue (RGB) light, converting them into corresponding drain current (I) states. By applying stochastic gate voltage (V) pulses to the IGZO phototransistor, the fluctuations are generated in these I states. When the I exceeds the threshold current (I), a spike signal is generated. This approach enables the conversion of light densities into spike signals, achieving spike-rate encoding. Moreover, adjusting the standard deviation (σ) of the V pulses controls the range of light densities converted into spike rates, while altering the mean (μ) of the V pulses changes the baseline level of spike rates. Remarkably, separate RGB channels offer a tunable encoding process, which can emphasize individual colors and correct color bias. The encoded spike rates are also fed into a spiking neural network (SNN) for CIFAR-10 pattern recognition, achieving an accuracy of 86%. The method allows the operation of SNN and shows the tunability in the process of light-to-spike encoding, opening possibilities for color image processing.
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http://dx.doi.org/10.1002/smtd.202401502 | DOI Listing |
Spectrochim Acta A Mol Biomol Spectrosc
September 2025
Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China. Electronic address:
To achieve ultrasensitive and real-time detection of the H1N1 influenza virus, this study designed a nucleic acid-free fluorescent biosensor based on 3D spherical DNA nanostructure and CRISPR/Cas12a (3D-SDNC). The biosensor constructs a rigid 3D nano-framework via self-assembly of six oligonucleotide chains, with H1N1-specific nucleic acid aptamers and Cas12a activator strands strategically positioned at multi-spined vertices for precise spatial coupling between viral recognition and signal transduction. Upon aptamer-virus binding, the induced conformational change liberates the activator strand, thereby activating the trans-cleavage activity of the Cas12a/crRNA complex to efficiently cleave the HEX/BHQ1 double-labeled fluorescent probe and initiate cascade signal amplification.
View Article and Find Full Text PDFBMJ Public Health
August 2025
Epidemiology and Data Management Unit, Division of Intramural Research, National Institute of Allergy and Infectious Diseases Division of Intramural Research, Bethesda, Maryland, USA.
Introduction: Immune-deficient/disordered people (IDP) elicit a less robust immune response to COVID-19 vaccination than the general US population. Despite millions of IDP at presumed elevated risk, few population-level studies of IDP have been conducted in the Omicron era to evaluate breakthrough infection-related outcomes.
Methods: We followed a prospective cohort of 219 IDP and 63 healthy volunteers (HV) in the USA from April 2021 (Alpha variant peak) to July 2023 (Omicron XBB variant peak).
Front Sports Act Living
August 2025
Department of Exercise and Sport Science, Faculty of Science, University of Phayao, Phayao, Thailand.
Background: Spiking is a decisive offensive action in elite women's volleyball, with variations in spike type, court zone, and timing influencing match outcomes. Understanding tactical and temporal dimensions of spiking can offer insights into offensive efficiency and performance consistency.
Methods: A total of 2,599 spike attempts were analyzed from 29 matches (108 sets) in the 2024 Women's Volleyball Nations League.
Diagn Microbiol Infect Dis
August 2025
Blood Center of Zhejiang Province, Hangzhou 310006, China.
This study analyzed the correlation between false-positive HIV ELISA results (using Bio-Rad reagents) and SARS-COV-2 antibody levels in 301 unpaid apheresis platelet donors with prior infection or vaccination, enrolled from Zhejiang Blood Center between February 1 and May 31, 2023. Trends in both the HIV ELISA false-positive rate and SARS-COV-2 antibody levels were assessed. The false-positive rate rose in early 2023, peaking at 0.
View Article and Find Full Text PDFJ Virol
September 2025
Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Unlabelled: Ongoing viral evolution in immunocompromised individuals with persistent infection may facilitate the evolution of SARS-CoV-2 and emergence of variants of concern (VOC). This study was conducted in the Western Cape Province of South Africa where the HIV prevalence is around 8%, with limited information on the frequency of persistent SARS-CoV-2 infection, the pattern of evolution in these individuals, and if these variants contribute to the diversity of circulating viruses. This study investigated 75 individuals with two or more SARS-CoV-2 diagnoses at least one month apart.
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