Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

More than 2 million older Americans from underrepresented racial and ethnic minority groups (URGs) have early-stage Alzheimer's disease and related dementias (ADRD). There are very few scalable recruitment strategies, particularly for Black older adults, to accelerate participation in ADRD research. The Indiana Alzheimer's Disease Research Center (IADRC) and its Community Advisory Board developed and implemented the innovative RAAISE-D Framework. This Framework informed the creation of community-first recruitment strategies designed to accelerate participation of Black older adults in ADRD research. Preliminary outcomes from its implementation included the doubling of Black adult enrollment (46, 13.4% to 101, 26.9%) from April 2020 to April 2024. Black adults were more likely to have normal cognition, be female, and ≤ 12 years of education than non-Hispanic White adults. The RAAISE-D Framework identified key concepts for URG focused recruitment strategies which successfully accelerated enrollment of Black adults in ADRD research and could be generalized to other URGs. HIGHLIGHTS: RAAISE-D Framework provides adaptable URG recruitment strategies. IADRC CAB-researcher partnership was the foundation of community-first methodology. RAAISE-D Framework doubled the Black enrollment in the IADRC in 4 years.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11848153PMC
http://dx.doi.org/10.1002/alz.14440DOI Listing

Publication Analysis

Top Keywords

recruitment strategies
20
raaise-d framework
16
black adults
12
scalable recruitment
8
participation black
8
alzheimer's disease
8
black older
8
older adults
8
accelerate participation
8
adults adrd
8

Similar Publications

Background: Poststroke cognitive impairment (PSCI) affects 30% to 50% of stroke survivors, severely impacting functional outcomes and quality of life. This study uses functional near-infrared spectroscopy (fNIRS) to assess task-evoked brain activation and its potential for stratifying the severity in patients with PSCI.

Method: A cross-sectional study was conducted at Nanchong Central Hospital between June 2023 and April 2024.

View Article and Find Full Text PDF

Traumatic brain injury (TBI) impairs attention and executive function, often through disrupted coordination between cognitive and autonomic systems. While electroencephalography (EEG) and pupillometry are widely used to assess neural and autonomic responses independently, little is known about how these systems interact in TBI. Understanding their coordination is essential to identify compensatory mechanisms that may support attention under conditions of neural inefficiency.

View Article and Find Full Text PDF

Self-enriching nanozyme with photothermal-cascade amplification for tumor microenvironment-responsive synergistic therapy and enhanced photoacoustic imaging.

Mater Today Bio

October 2025

Yunnan Key Laboratory of Breast Cancer Precision Medicine, Institute of Biomedical Engineering, Kunming Medical University, Kunming, 650500, Yunnan, China.

Achieving precise intratumoral accumulation and coordinated activation remains a major challenge in nanomedicine. Photothermal therapy (PTT) provides spatiotemporal control, yet its efficacy is hindered by heterogeneous distribution of PTT agents and limited synergy with other modalities. Here, we develop a dual-activation nanoplatform (IrO-P) that integrates exogenous photothermal stimulation with endogenous tumor microenvironment (TME)-responsive catalysis for synergistic chemodynamic therapy (CDT) and ferroptosis induction.

View Article and Find Full Text PDF

Introduction: Organizational resilience is of paramount importance for coping with adversity, particularly in the healthcare sector during crises. The objective of the present study was to evaluate the impact of resilience-based interventions on the well-being of healthcare employees during the pandemic. In this study, resilience-based interventions are defined as organizational actions that strengthen a healthcare institution's capacity to cope with crises-such as ensuring adequate personal protective equipment and staff testing, clear risk-communication, alternative care pathways (e.

View Article and Find Full Text PDF

Mitigating Fox Predation on Freshwater Turtle Nests: Comparing Effectiveness of Three In Situ Protection Methods.

Ecol Evol

September 2025

Department of Ecological, Plant & Animal Sciences Centre for Freshwater Ecosystems, School of Agriculture, Biomedicine and Environment, La Trobe University, Albury-Wodonga Campus West Wodonga Victoria Australia.

Freshwater turtles in the Murray-Darling Basin (MDB), Australia, have declined since the 1970s. Intense nest predation by introduced foxes likely contributes to these declines, disrupting juvenile recruitment needed to sustain populations. Traditional lethal control methods, such as baiting and shooting, have proven inadequate, highlighting the need for innovative conservation strategies.

View Article and Find Full Text PDF