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The lack of early assessment tools for swallowing function in patients in the intensive care unit (ICU) may lead to delays in oral intake. This study assessed the effectiveness of a new bedside swallowing screening tool in detecting dysphagia in patients in the ICU or isolation settings, where isolation settings refer to conditions such as COVID-19, where patient mobility is limited. We assessed swallowing function in 13 patients with severe acute respiratory distress syndrome. To ensure patient safety, a bedside preliminary investigation was performed to assess the patient's alertness level, and ultrasound findings of the vocal cords were obtained. Patients were nasogastric(NG) tube feeding or fasted if they did not meet a certain readiness level. Additionally, patients who passed the preliminary investigation underwent methylene blue dye or citric acid swallowing tests if they had or had not undergone tracheostomy, respectively. The Gugging Swallowing Screen (GUSS) test was used to determine whether an oral diet was appropriate. Of the 13 patients, 1 failed to meet the criteria during the preliminary examination, and 12 underwent the examination and initiated oral intake. Significant differences were found in the GUSS scores between the tracheostomy and non-tracheostomy groups but not in the examination validity. NG tube was implemented if the examination criteria were not met at each stage. Patients who passed the newly developed dysphagia screening tool exhibited no aspiration symptoms post-oral feeding initiation, enabling their discharge. In conclusion, the proposed screening test can be performed safely and easily, allowing for early dysphagia detection, reduced aspiration risk, and safe oral feeding in patients in the ICU or isolation settings.
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http://dx.doi.org/10.1007/s00455-024-10784-1 | DOI Listing |
BMC Public Health
September 2025
Department of Medicine, Huddinge, Karolinska Institutet, 141 83, Huddinge, Sweden.
Background: Preschools are important environments in shaping young children's lifestyle behaviours, including movement (physical activity, screen time, and sleep) and eating behaviours. Few studies have investigated how teachers and principals can be supported in promoting healthy lifestyle behaviours in the preschool setting and whether a digital support tool could be a way forward. This study aimed to explore preschool teachers' and principals' perceptions, needs, and prerequisites for promoting healthy lifestyle behaviours, as well as their preferences for a potential digital support.
View Article and Find Full Text PDFBMC Musculoskelet Disord
September 2025
Department of Clinical Sciences at Danderyds Hospital, Department of Orthopedic Surgery, Karolinska Institutet, Stockholm, 182 88, Sweden.
Background: This study evaluates the accuracy of an Artificial Intelligence (AI) system, specifically a convolutional neural network (CNN), in classifying elbow fractures using the detailed 2018 AO/OTA fracture classification system.
Methods: A retrospective analysis of 5,367 radiograph exams visualizing the elbow from adult patients (2002-2016) was conducted using a deep neural network. Radiographs were manually categorized according to the 2018 AO/OTA system by orthopedic surgeons.
Clin Rheumatol
September 2025
Immunology Market Access, Johnson & Johnson, Horsham, PA, USA.
Introduction/objective: Oral glucocorticoids (OGC) are conventionally used as first-line treatment for dermatomyositis (DM) and polymyositis (PM). This study evaluated clinical and economic outcomes associated with long-term (LT) OGC use in DM/PM.
Methods: Adults with ≥ 2 medical claims of DM/PM 30‒365 days apart from January 1, 2016, to December 31, 2022, and ≥ 1 diagnosis code of a physician specialty of interest were selected from the MarketScan Commercial and Medicare Supplemental databases.
Eur Radiol Exp
September 2025
Center for MR-Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in an improved agreement in lung volume measurements determined by different raters, also known as inter-rater reliability.
Materials And Methods: In this single-center retrospective study, fetal lung volumes calculated from both SR reconstructions and the original images were analyzed.
NPJ Precis Oncol
September 2025
Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Breast cancer is a highly heterogeneous disease with diverse outcomes, and intra-tumoral heterogeneity plays a significant role in both diagnosis and treatment. Despite its importance, the spatial distribution of intra-tumoral heterogeneity is not fully elucidated. Spatial transcriptomics has emerged as a promising tool to study the molecular mechanisms behind many diseases.
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