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Background: Ms. S was a 50-year-old woman hospitalized with necrotizing fasciitis from a labial abscess. After several surgical interventions wound debridements were performed consecutively for 6 days. She was left with extensive full thickness tissue destruction of her abdomen, bilateral groin areas, and complete displacement of skin over her mons pubis. Wounds related to necrotizing fasciitis can be especially challenging to manage, especially when the perineal region is involved. Due to the location of such wounds, it can be difficult to maintain dressings, including negative pressure wound therapy with instillation devices (NPWTi). Ms. S. also had a history of uncontrolled diabetes mellitus, which can hinder wound healing.
Case: The Wound, Ostomy and Continence (WOC) nurse was consulted on day 6 of Ms. S's admission, for application of NPWTi. Complex NPWTi dressings were completed in the operating room (OR), 2 times weekly for 2 weeks. When Ms. S was transferred from the intensive care unit to the surgical unit, NPWT dressings with instillation were used but later converted to standard NPWT, changed twice weekly by the WOC nurse. Dressings were changed at the bedside until day 29 of her admission.
Conclusion: The management of Ms. S's extensive wounds was successful, and her wounds were closed by plastic surgery on day 29 of her admission. Ms. S was the first patient at our hospital with extensive wounds from necrotizing fasciitis to undergo surgical closure of her wounds during the same hospital admission.
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http://dx.doi.org/10.1097/WON.0000000000001101 | DOI Listing |
Laryngoscope
September 2025
Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Weill Cornell Medical Center, New York, New York, USA.
We report the case of a 3-month-old infant with methicillin-resistant Staphylococcus aureus (MRSA) necrotizing fasciitis of the neck and chest complicated by bacteremia, pneumonia, and mediastinitis, which required multiple surgical debridements, including median sternotomy. The case is unsual given the patient's age and causative pathogen, and underscores the importance of early diagnosis, timely surgical intervention, and multidisciplinary collaboration to ensure survival.
View Article and Find Full Text PDFInfect Drug Resist
September 2025
Department of Infection Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, People's Republic of China.
This study presents a rare case of severe acute bacterial skin and soft tissue infection (ABSSSI) following freshwater fish spike injury in a 73-year-old man. Within 24 hours of sustaining the wound, the patient developed septic shock and progressive necrotizing fasciitis. Despite early administration of broad-spectrum antibiotics and intensive care, his condition deteriorated, necessitating below-the-elbow amputation on hospital day four.
View Article and Find Full Text PDFKlin Mikrobiol Infekc Lek
June 2025
Department of Infectious Diseases and Travel Medicine, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic, e-mail:
Skin and soft tissue infections (SSTIs) represent a diverse spectrum of conditions, including erysipelas, cellulitis, cutaneous abscesses, necrotizing fasciitis, and myonecrosis. Erysipelas and cellulitis are the most common community-acquired SSTIs. Erysipelas is typically caused by pyogenic streptococci, while cellulitis often has a staphylococcal etiology.
View Article and Find Full Text PDFActa Diabetol
September 2025
Department of Systems of Medicine, University of Tor Vergata, Rome, 00133, Italy.
Aim: The study aimed to evaluate the rate and causes of major amputation in patients with diabetic foot syndrome.
Methods: The current study is a retrospective observational study including consecutive patients referred to a tertiary-level diabetic foot service from January 2020 to November 2023 due to a new diabetic foot problem requiring hospital admission. All patients had been managed by a multi-disciplinary diabetic foot team (MDFT) through a pre-set limb salvage protocol including the management of peripheral arterial disease, infection, foot offloading, and comorbidities.
J Med Case Rep
August 2025
Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, People's Republic of China.
Background: Pyogenic liver abscesses are a fatal condition often seen in emergency departments. The major clinical presentations include weakness, anorexia, fever, chills, ventosity and abdominal pain. They occur in immunocompromised individuals who suffer from diabetes mellitus, malignant tumors, hepatocirrhosis, kidney failure, and solid organ transplantation, or those with long-term administration of glucocorticoids.
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