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Publications of living systematic reviews (LSRs) are increasing rapidly. Guidance facilitating transparent, complete, and accurate reporting of LSRs is needed. This paper reports the development of an extension of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 statement for LSRs (PRISMA-LSR). The PRISMA-LSR extension includes the PRISMA-LSR checklist, the PRISMA-LSR flow diagram, reporting recommendations for the LSR status, and an explanation and elaboration document. This extension has been developed as an “add-on” to the PRISMA 2020 statement, meaning it should be used in addition to the PRISMA 2020 statement. The PRISMA-LSR extension is expected to benefit authors, editors, peer reviewers, and users of LSRs through transparent, complete, and accurate reporting of LSRs.
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http://dx.doi.org/10.1136/bmj-2024-079183 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
Neurosurgery Department, 10th Military Research Hospital and PolyClinic SPZOZ, Bydgoszcz, Poland.
Background: Pheochromocytoma (PCC) is a rare neuroendocrine tumor, with 10-15% of cases showing malignant behavior defined by metastatic spread, including exceptionally rare central nervous system (CNS) involvement. Brain metastases present unique diagnostic and therapeutic challenges due to their potential to impair neurological function. This study reports a case of malignant PCC (mPCC) with CNS metastases and a systematic review to clarify the clinical patterns, management strategies, and prognostic factors.
View Article and Find Full Text PDFClin Pharmacol
September 2025
Department of Biology, College of Science Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Cancer remains the second leading cause of death worldwide, highlighting the urgent need for novel therapeutic approaches. Fungi are a rich source of bioactive metabolites, some of which exhibit potent anticancer properties. This scoping review evaluates the current research on fungal metabolites with anticancer potential, focusing on species native to Saudi Arabia's unique ecosystem.
View Article and Find Full Text PDFBarriers such as stigma and limited access to care continue to impede treatment for anxiety disorders. Telemedicine has emerged as a promising alternative to in-person psychological interventions, particularly after the COVID-19 pandemic. This systematic review compares the efficacy of telemedicine and in-person therapies for anxiety disorders, evaluating outcomes, patient engagement, and methodological rigor.
View Article and Find Full Text PDFNurse Educ Pract
September 2025
School of Nursing, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Aim: This study aimed to systematically review and synthesize the most recent qualitative studies on frontline nurses' insights and perspectives regarding the use of artificial intelligence (AI) tools in their clinical practice in hospital settings.
Background: There is limited information on frontline nurses' perceptions, attitudes and expectations regarding the adoption of AI in healthcare.
Design: A systematic review and thematic synthesis of qualitative evidence was conducted.
J Refract Surg
September 2025
From the Department of Ophthalmology at University of São Paulo, São Paulo, Brazil.
Purpose: To analyze stabilization results using various standard and accelerated corneal cross-linking (CXL) protocols in patients younger than 18 years.
Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 guidelines. A bibliographic search was carried out based on PubMed and Scopus data, with the last being performed in December 2024.