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Objective: Sexual minority college students have higher alcohol use and alcohol-related consequences than heterosexual students. Peers are salient determinants of young adult drinking, and examining social network characteristics is useful for understanding peer influence. This study used social network methods to understand network characteristics, alcohol use (i.e., maximum drinks), and alcohol consequences of sexual minority and heterosexual college students.
Method: Sexual minority and heterosexual junior-year college students ( = 1,150) were compared on (a) social network features (eigenvector centrality, indegree, outdegree, mutuality, closeness) and (b) alcohol use and consequences. We also determined (c) whether social network characteristics were associated with alcohol use and consequences and (d) whether these associations differed based on sexual identity or attraction.
Results: Students reporting a bisexual identity or same-gender attraction had greater eigenvector centrality (global popularity or prestige) than heterosexual students or those reporting exclusively other-gender attraction, respectively. Students reporting same-gender attraction had higher outdegree (expansiveness) and more reciprocated ties (mutuality) than individuals reporting exclusively other-gender attraction, but heterosexual students and students with other-gender attraction reported higher relationship closeness; they also reported a higher number of drinks than bisexual students and students with same-gender attraction. One significant interaction showed that outdegree (expansiveness) was associated with alcohol consequences for students who reported any same-gender attraction but not for students who reported exclusively opposite-gender attraction.
Conclusions: Sexual minority college students' greater network prominence differs from research with adolescents and might reflect students' efforts to establish more affirming social connections in a college environment.
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http://dx.doi.org/10.15288/jsad.24-00119 | DOI Listing |
Nat Protoc
September 2025
Pharmacomicrobiomics Research Center and College of Pharmacy, Hanyang University, Ansan, Republic of Korea.
Metabolism is a fundamental process that shapes the pharmacological and toxicological profiles of drugs, making metabolite identification and analysis critical in drug development and biological research. Global Natural Products Social Networking (GNPS) is a community-driven infrastructure for mass spectrometry data analysis, storage and knowledge dissemination. GNPS2 is an improved version of the platform offering higher processing speeds, improved data analysis tools and a more intuitive user interface.
View Article and Find Full Text PDFBMJ Open
September 2025
Radiotherapy Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, England, UK.
Introduction: There are estimated to be 3.4 million patients in the UK living after a diagnosis of cancer. We know very little about their quality of life or healthcare usage.
View Article and Find Full Text PDFJ Oral Pathol Med
September 2025
Department of Pediatric Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Background: Oral and plunging ranulas require effective treatment strategies to minimize recurrence; yet no consensus exists on the most effective approach.
Objectives: This systematic review evaluated several treatments for the recurrence of oral and plunging ranulas.
Methodology: A comprehensive search was conducted in five bibliographic databases and gray literature.
Exp Clin Endocrinol Diabetes
August 2025
Department of Endocrinology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.
Painful diabetic neuropathy (PDN), a severe microvascular complication of diabetes, is closely associated with neuroinflammation. This study aimed to investigate the mechanism of circ_0002590 in neuroinflammation associated with PDN.The Schwann cells (HEI193) were treated with high glucose (HG, 150 mM) to simulate the diabetic microenvironment.
View Article and Find Full Text PDFJMIR Cancer
September 2025
Department of Health Outcomes and Biomedical Informatics, University of Florida, 1889 Museum Road, Suite 7000, Gainesville, FL, 32611, United States, 1 352 294-5969.
Background: Disparities in cancer burden between transgender and cisgender individuals remain an underexplored area of research.
Objective: This study aimed to examine the cumulative incidence and associated risk factors for cancer and precancerous conditions among transgender individuals compared with matched cisgender individuals.
Methods: We conducted a retrospective cohort study using patient-level electronic health record (EHR) data from the University of Florida Health Integrated Data Repository between 2012 and 2023.