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Introduction: This study quantitatively evaluated the understandability and actionability of webpages for patients undergoing hemodialysis (HD).
Methods: In June 2022, we searched on Google and Yahoo Japan using the top five keywords associated with end-stage kidney disease and HD to identify relevant materials. Subsequently, we used the Japanese version of the Patient Education Materials Assessment Tool to assess the understandability and actionability of these materials, rating them on a scale from 0% to 100%. The threshold was set at 70%.
Results: Among the included 194 materials, the overall understandability was 66.7%, and the actionability was 33.3%. Only 38.7% and 16.5% of the materials were deemed understandable and actionable, respectively. Challenges included the need for plain language and concise summaries to improve understandability, along with the use of effective visual aids for actionability.
Conclusion: This study suggests that existing webpages on HD are not presented in a manner that patients can utilize.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879477 | PMC |
http://dx.doi.org/10.1111/1744-9987.14221 | DOI Listing |
Transl Oncol
September 2025
Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan. Electronic address:
Liquid biopsies, particularly those involving circulating tumor DNA (ctDNA) from patient blood, have emerged as crucial and minimally invasive adjuncts to standard tissue-based testing. ctDNA testing enables the identification of actionable mutations for targeted therapy and can be routinely used when tissue samples are unavailable for genotyping. Compared to tissue-based testing, ctDNA testing has the advantages of capturing spatial or temporal genomic heterogeneity and facilitating repeated assessments.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
University Sains Malaysia, 11800, Penang, Malaysia; Berlin School of Business and Innovation (BSBI), Berlin, Germany. Electronic address:
This study examines the impact of AI-enhanced transformational leadership on IT professional burnout among Chinese IT professionals while investigating the mediating role of AI learning self-efficacy and the moderating effects of AI-enabled work practices and organizational AI-communication adequacy. Drawing on the technology-organization-environment (TOE) Framework, our research integrates traditional transformational leadership with emerging AI applications, offering a comprehensive model for understanding how digital leadership influences employee well-being in high-pressure IT environments. Data collected from 511 IT professionals across major Chinese technology hubs were analyzed using SMART-PLS.
View Article and Find Full Text PDFInt J Obstet Anesth
August 2025
Department of Liver Transplant Anaesthesia, Institute of Liver and Biliary Sciences, New Delhi, India.
Background: Epidural analgesia is the gold standard for labor pain relief, yet performing patient education remains challenging due to time constraints, language barriers, and variable health literacy. Traditional educational approaches often fail to ensure adequate patient understanding. Artificial intelligence (AI) interactive avatars offer a novel solution for delivering standardized, empathetic, and accessible patient education.
View Article and Find Full Text PDFAcad Radiol
September 2025
Associate Professor of Radiology, University of Pennsylvania, Philadelphia, PA 19146 (S.J.). Electronic address:
Rationale And Objectives: To understand how an imperfect surrogate can lead to defensive medicine.
Materials And Methods: Historical analysis was performed on electronic fetal monitoring.
Results: Electronic Fetal Monitoring is an example of a flawed surrogate.
Biochim Biophys Acta Rev Cancer
September 2025
Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, Bradford, United Kingdom. Electronic address:
Cancer stem cells (CSCs) are central to tumour initiation, progression, and relapse, yet their dynamic and adaptive nature hampers therapeutic targeting. Once viewed as a fixed subpopulation, CSCs are now recognised as a fluid functional state that tumour cells can enter or exit, driven by intrinsic programs, epigenetic reprogramming, and microenvironmental cues. This plasticity complicates identification due to inconsistent marker expression and enables resistance, dormancy, and metastasis.
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