98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11489521 | PMC |
http://dx.doi.org/10.1016/j.ekir.2024.07.037 | DOI Listing |
Ther Clin Risk Manag
September 2025
Department of Anesthesiology, The Second Affiliated Hospital of Guilin Medical University, Guilin, People's Republic of China.
Clin Optom (Auckl)
September 2025
Department of Orthoptics, Faculty of Medical Technology, Teikyo University, Itabashi-ku, Tokyo, Japan.
Trauma Surg Acute Care Open
September 2025
Department of Clinical Research and Leadership, PhD Program in Translational Health Sciences, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
Acta Anaesthesiol Scand
October 2025
Centre for Anaesthesiological Research, Department of Anaesthesiology, Zealand University Hospital, Køge, Denmark.
Background: Multiple organ dysfunction syndrome (MODS) in critical illness involves dysregulated immune and inflammatory responses, endotheliopathy, and coagulation activation. We investigated how three types of endotheliopathy biomarkers relate to pro- and anti-inflammatory responses and clinical outcomes in intensive care unit (ICU) patients.
Methods: In this secondary, explorative analysis of a prospective single-centre cohort (n = 459), we assessed associations between endotheliopathy biomarkers (syndecan-1, soluble thrombomodulin (sTM), platelet endothelial cell adhesion molecule-1 (PECAM-1)) and inflammatory biomarkers (pro-inflammatory: IFN-ϒ, IL-1β, IL-2, IL-6, IL-8, IL-12p70, TNF-α; anti-inflammatory: IL-4, IL-10, IL-13) at ICU admission using linear regression.
Neurocrit Care
September 2025
Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.